Hoff, H. F.; Gottolb, R.
September 1969
Angiology;Sep1969, Vol. 20 Issue 8, p446
Academic Journal
The article discusses regeneration in large blood vessels following mild mechanical trauma. Earlier investigations have showed distinct differences in the morphologically characterized changes between hard and mild mechanical trauma on blood vessels with light microscopy of silver-stained surface preparations. Whereas hard mechanical trauma, induced by ligation of the vessel wall with thick silk thread, produced complete endothelial cell destruction at the ligated area and eventual overgrowth by regenerating endothelial cells, mild mechanical trauma induced by compressing the vessel wall with a clamp covered by rubber tubing was characterized by early focal endothelial injury, eventual formation of multinucleated endothelial cells and endothelial phagocytosis of blood cell degradation products.


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