TITLE

EFFECT OF BRADYKININ AND ELEDOISIN ON THE REGIONAL CIRCULATION

AUTHOR(S)
Nakano, Jiro; Kusakari, Takashi
PUB. DATE
May 1966
SOURCE
Angiology;May1966, Vol. 17 Issue 5, p333
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The effects of synthetic bradykinin and eledoisin on the peripheral circulation were studied in hind limbs of anesthetized dogs. It was found that the intraarterial injection of either peptide caused marked decreases in the femoral arterial perfusion pressure and the femoral arterial peripheral resistance, whereas these peptides increased the femoral venous outflow, even when the femoral arterial inflow was kept constant and systemic arterial pressure remained essentially unchanged. The present observation indicates that bradykinin and eledoisin dilate both arterioles and arteroveous communication vessels in canine hind limbs.
ACCESSION #
16369525

 

Related Articles

  • Effects of ageing and fitness on skin-microvessel vasodilator function in humans. Tew, Garry A.; Klonizakis, Markos; Saxton, John M. // European Journal of Applied Physiology;May2010, Vol. 109 Issue 2, p173 

    The impact of cardiopulmonary fitness ( $$ \dot{V} $$O2max) on the age-related decline in skin-microvessel vasodilator function has not been fully established and the inter-relationships among different measures of microvascular vasodilator function are unknown. We used laser Doppler flowmetry...

  • Using skin temperature gradients or skin heat flux measurements to determine thresholds of vasoconstriction and vasodilatation. House, James R.; Tipton, Michael J. // European Journal of Applied Physiology;Oct2002, Vol. 88 Issue 1/2, p141 

    Forearm–fingertip skin temperature differentials (Tsk-diff) are used to indicate vasomotor tone, vasoconstriction defined as having occurred when Tsk-diff≥4°C (Sessler et al. 1987, 1988a, b). This study was conducted to determine whether Tsk-diff or finger pad heat flux (HF) can...

  • Effect of local heating and vasodilation on the cutaneous venoarteriolar response. Davison, Jennifer; Short, Daniel; Wilson, Thad // Clinical Autonomic Research;Dec2004, Vol. 14 Issue 6, p385 

    The cutaneous venoarteriolar response (CVAR) is a local non-adrenergic vasoconstrictor reflex that is engaged via increases in local transmural pressure. The purpose of this study was to determine if local temperature alters the vasoconstrictor ability of the CVAR. Twelve (5 male, 7 female)...

  • Pharmacologic Vasodilation. Spáčil, J.; Linhart, J. // Angiology;Apr1980, Vol. 31 Issue 4, p254 

    The article discusses a clinical case of pharmacologic vasodilation. Prolonged measurement of foot blood flow with the mechanical plethysmograph filled with air or water may be inconvenient to some patients. Since the present study required flow measurements over a period of 4 hours, it was...

  • Beneficial Effect of Papaverine Plus Raubasine in Peripheral Arterial Insufficiency. Brevetti, Gregorio; Chiariello, Massimo; Verrienti, Salvatore; Spena, Michele; Desiderati, Maurizio; Condorelli, Mario // Angiology;Aug1983, Vol. 34 Issue 8, p517 

    It has been demonstrated that, in most arteriopathic patients, vasodilators induce the vascular steal phenomenon, i.e. the shunting of blood from the ischemic to the normally perfused areas. It is conceivable, therefore, that vasoconstrictors may improve in the opposite way, reducing the blood...

  • Bradykinin causes inhibition of methacholine-induced bronchoconstriction in vivo in mice. Folkerts, Gert; van Heuven-Nolsen, Dicky; Nijkamp, Frans P. // Naunyn-Schmiedeberg's Archives of Pharmacology;Jul2001, Vol. 364 Issue 1, p53 

    In this study the influence of bradykinin on airway responses was investigated in anaesthetised and ventilated mice. Airway resistance in mice was monitored using whole body plethysmography. Intravenous (i.v.) administration of bradykinin (4–40 µg/kg) did not cause a direct effect on...

  • cardiovascular collapse.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p371 

    A definition of the term "cardiovascular collapse" which refers to the sudden loss of blood flow to the brain and other organs is presented.

  • Potential role of kinins in the effects of taurine in high-fructose-fed rats. Nandhini, A. T. Anitha; Thirunavukkarasu, V.; Anuradha, C. V. // Canadian Journal of Physiology & Pharmacology;Jan2004, Vol. 82 Issue 1, p1 

    The present work investigates the involvement of kinins in the effects of taurine in fructose-fed hypertensive rats. The effects of taurine on blood pressure, plasma glucose, insulin, and the insulin sensitivity index were determined. Angiotensin-converting enzyme (ACE) activity and nitrite...

  • Increased Kinin Levels and Decreased Responsiveness to Kinins During Aging. Pérez, Viviana; Velarde, Victoria; Acuña-Castillo, Claudio; Gómez, Christian; Nishimura, Sumiyo; Sabaj, Valeria; Walter, Robin; Sierra, Felipe // Journals of Gerontology Series A: Biological Sciences & Medical ;Aug2005, Vol. 60 Issue 8, p984 

    Kinins are vasoactive peptides released from precursors called kininogens, and serum levels of both T- and K-kininogens increase dramatically as rats age. Kinin release is tightly regulated, and here we show that serum kinin levels also increase with age, from 63 ± 16 nmol/L in young Fisher...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics