TITLE

TESTOSTERONE THERAPY IN OBLITERATING ARTERIAL LESIONS IN THE LOWER LIMBS

AUTHOR(S)
Dohn, Kai; Hvidt, Vald; Nielsen, John; Palm, Leif
PUB. DATE
June 1968
SOURCE
Angiology;Jun1968, Vol. 19 Issue 6, p342
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article presents a study that examines the effect of testosterone therapy in obliterating arterial lesions in lower limbs. It has been demonstrated by animal experiments that a basic effect of the sex hormones is hyperemization of the whole organism. In studies using animal experiments it has been possible to demonstrate a hyperemitising effect of both estrogenic and androgenic hormones. Large doses of ergotamine tartrate cause necrosis of the tail in white rats, and this can be counteracted to a large degree by the simultaneous administration of sex hormones. The article presents a study that examines the effect of testosterone therapy in obliterating arterial lesions in lower limbs. It has been demonstrated by animal experiments that a basic effect of the sex hormones is hyperemization of the whole organism. In studies using animal experiments it has been possible to demonstrate a hyperemitising effect of both estrogenic and androgenic hormones. Large doses of ergotamine tartrate cause necrosis of the tail in white rats, and this can be counteracted to a large degree by the simultaneous administration of sex hormones.
ACCESSION #
16369478

 

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