TITLE

PRELIMINARY OBSERVATIONS ON THE VALUE OF DIAZOXIDE ADMINISTERED INTRAVENOUSLY IN MAN

AUTHOR(S)
Kakaviatos, Nikos; Finnerty Jr., Frank A.
PUB. DATE
November 1962
SOURCE
Angiology;Nov1962, Vol. 13 Issue 11, p541
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Diazoxide, a nondiuretic thiazide, was administered intravenously to 55 hypertensive patients. Two hundred to 300 mg resulted in prompt reduction of arterial pressure (within 1 to 2 min.), increase in cardiac output and decrease in total peripheral resistance. There were no signs of collapse or cerebral ischemia. The duration of action was 2 to 3 hr. If the duration of action could be prolonged diazoxide would be considered an ideal agent for the treatment of hypertensive emergencies.
ACCESSION #
16369338

 

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