Peracchia, C.; Vassallo, C.
July 1966
Angiology;Jul1966, Vol. 17 Issue 7, p451
Academic Journal
Electron microscopy has revealed marked and typical modifications of collagen in the part of the artery affected by Buerger's disease. Thickening of the fibrils due to dissociation of the subfilaments and their fragmentation and disintegration into an amorphous substance are described. The close similarity between these alterations of collagen fibrils in the arteries and the ones previously observed in the collagen of the ganglia has led us to put forward the hypothesis that there is a systematic development in this disease based on a particular lesion of collagen.


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