TITLE

Lower Extremity Blood Flow in Intermittent Claudication -- The Role of Oral Glucose Tolerance Test

AUTHOR(S)
Hanson, Martin
PUB. DATE
October 1987
SOURCE
Angiology;Oct1987, Vol. 38 Issue 10, p756
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Tobacco smoking is a risk factor for peripheral arterial disease. During oral glucose tolerance tests (OGTT) in a population study the author and co-workers have earlier shown that smokers have higher blood glucose values early postload and lower values at two hours compared with nonsmokers. Eighty-three patients, all with intermittent claudication but with a normal. OGTT, have now been studied according to their response to an oral glucose load. The blood flow resistance during reactive hyperemia, as measured with a calf plethysmograph, was compared between subjects in the quartile of patients with the highest forty-five-minute blood glucose and those in the lowest quartile. The blood flow resistance was significantly higher in the group with a high forty-five-minute blood glucose, 13.3 ± 1.34 vs 9.5 ± 0.65 (mean ± SEM), p < 0.02. Blood pressure and blood lipids were similar in the two groups. It is suggested that an exaggerated early response in the OGTT might be an independent risk factor for peripheral arterial disease.
ACCESSION #
16366629

 

Related Articles

  • Leg Blood Flow in Intermittent Claudication -- A Comparison Between Non Insulin Dependent Diabetics and Non Diabetics. Janzon, Lars; Bergentz, Sven-Erik; Ericsson, Bjorn F.; Hanson, Martin; Lindell, Sven-Eric // Angiology;Nov1984, Vol. 35 Issue 11, p724 

    The influence of diabetes on leg blood flow in intermittent claudication has been assessed by comparing the systolic arm-ankle pressure gradient at rest and resistance to blood flow during reactive hyperemia in patients with non-insulin dependent diabetes and non-diabetic controls. Cases and...

  • claudication.  // Taber's Cyclopedic Medical Dictionary (2009);2009, Issue 21, p464 

    A definition of the medical term "claudication," which refers to lameness characterized by shiny skin over the limb with decreased blood flow, is presented.

  • Association of passive and active smoking with incident type 2 diabetes mellitus in the elderly population: the KORA S4/F4 cohort study. Kowall, Bernd; Rathmann, Wolfgang; Strassburger, Klaus; Heier, Margit; Holle, Rolf; Thorand, Barbara; Giani, Guido; Peters, Annette; Meisinger, Christine // European Journal of Epidemiology;Jun2010, Vol. 25 Issue 6, p393 

    Active smoking is a risk factor for type 2 diabetes (T2DM), but it is unclear whether exposure to environmental tobacco smoke (ETS) is also associated with T2DM. The effect of passive and active smoking on the 7-year T2DM incidence was investigated in a population-based cohort in Southern...

  • Intermittent claudication: factors determining outcome. Hughson, W.G.; Mann, J.I.; Tibbs, D.J.; Woods, H.F.; Walton, I. // British Medical Journal;5/27/1978, Vol. 1 Issue 6124, p9 

    Two groups of patients were followed up for four to eight years after first referral or admission to hospital for intermittent claudication (IC) in a study of the natural history of the disease and of factors determining its outcome. In one series of 60 patients, those who stopped or reduced...

  • claudication. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p177 

    A definition of the term "claudication" is presented. This refers to a muscle pain, particularly in the legs, which is caused by an inadequate supply of blood as a result of narrowing of arteries. Aside from atherosclerosis, another cause is spinal stenosis.

  • Effects of Tobacco Smoke Inhalation on Capillary Blood Flow in Human Skin. Richardson, Daniel // Archives of Environmental Health;Jan/Feb87, Vol. 42 Issue 1, p19 

    Examines the effects of tobacco smoke inhalation on capillary blood flow (CBF) in human skin. Effect of increased nicotine levels on the trend in CBF; Reduction of CBF through tobacco smoke inhalation; Differences between changes in the cutaneous CBF in tobacco smoking and smoke inhalation.

  • Smoking during pregnancy and risk of abnormal glucose tolerance: a prospective cohort study. Haskins, Amy E.; Bertone-Johnson, Elizabeth R.; Pekow, Penelope; Carbone, Elena; Fortner, Renée T.; Chasan-Taber, Lisa // BMC Pregnancy & Childbirth;2010, Vol. 10, p55 

    Background: Disturbances in glucose metabolism during pregnancy are associated with negative sequalae for both mother and infant. The association between smoking and abnormal glucose tolerance (AGT) remains controversial. Therefore, the aim of this study was to examine the relationship between...

  • PARADOXICAL EFFECT ON PERIPHERAL BLOOD FLOW AFTER SYMPATHETIC BLOCKADES IN PATIENTS WITH GANGRENE DUE TO ARTERIOSCLEROSIS OBLITERANS. Uhrenholdt, A.; Dam, W. H.; Larsen, O. Andree; Lassen, N. A. // Vascular Surgery;May/Jun1971, Vol. 5 Issue 3, p154 

    A total of 61 lumbar sympathetic blockades were performed on 5 patients with gangrene on one or several toes and on 6 patients with intermittent claudication only. Subcutaneons blood flow on the dorsum of the foot was measured by the Xenon clearance technique before and after the blockades. In...

  • Proteinuria in a placebo-controlled study of basic fibroblast growth for intermittent claudication. Cooper Jr., Leslie T.; Hiatt, William R.; Creager, Mark A.; Regensteiner, Judith G.; Casscells, Ward; Isner, Jeffrey M.; Cooke, John P.; Hirsch, Alan T. // Vascular Medicine;2001, Vol. 6 Issue 4, p235 

    Examines the occurrence of basic fibroblast growth factor (bFGF)-related proteinuria for intermittent claudication in patients with peripheral arterial disease. Intravenous administration of bFGF; Association of limb blood flow with exercise; Ways of improving claudication symptoms.

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics