Tanyol, H.
December 1964
Angiology;Dec1964, Vol. 15 Issue 12, p539
Academic Journal
1. As a result of the observation on the frequent development of portal cirrhosis in individuals with primary varicose veins, a genetic link between these two conditions was suggested. In subsequent studies, patients with primary varicose veins were scanned for manifestations seen frequently in cirrhosis, such as spider angiomas, liver palm, white nail and scantiness of body hair. 2. Of these four stigmas only scantiness of body hair appeared to be associated with varicose veins. In 14 male patients with varicose veins and in 20 control subjects, the average number of hairs per 4 cm2 of 16 predetermined body areas was 13 and 32, respectively. This difference is highly significant statistically. 3. Hypotrichosis, when present, appeared to be a lifelong characteristic of these individuals and was tint traceable to any acquired disturbance, endocrine or otherwise. 4. In view of the known role of blood supply in hair growth, it seems reasonable to attribute the association of hypotrichosis with varicose veins and portal cirrhosis to a possible inborn systemic vascular anomaly underlying these three conditions.


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