Laser-Doppler Examinations in Persons with Healthy Vasculature and in Patients with Peripheral Arterial Occlusive Disease ,

Ranft, J.; Heidrich, H.; Peters, A.; Trampisch, H.
November 1986
Angiology;Nov1986, Vol. 37 Issue 11, p818
Academic Journal
Recently, a new procedure for noninvasive measurement of the microcirculation has been developed in the form of a helium-neon-laser Doppler apparatus with which the total erythrocyte flow through a cubic millimeter of skin is quantifiable. The authors used the procedure to examine 17 persons with healthy vessels, 36 patients with a degenerative occlusive disease of the peripheral arteries in Fontaine stages II-IY, and 5 patients with endangiitis obliterans. It is concluded that single measurements do not permit an assessment of microcirculatory conditions but that provocative tests (which are described), especially occlusion tests, make possible valid and reproducible statements and have a high selectivity with respect to the different stages of disease. By repeated measurements followed by calculation of mean values, a further reduction in intraindividual variability among the measurement results can be obtained. Laser-Doppler examinations of the skin constitute a new procedure with which quantitative statements on the blood flow through skin are feasible and from which interesting results can be expected, especially when used as an acute test.


Related Articles

  • Blood Flow Measurement by Laser Doppler Method in Orofacial Region. Grga, Djurica; Dželetovic, Bojan; Živkovic, Slavoljub; Kršljak, Elena // Serbian Dental Journal / StomatoloÅ¡ki Glasnik Srbije;Sep2010, Vol. 57 Issue 3, p141 

    No abstract available.

  • Merenje protoka krvi laser dopler metodom u orofacijalnoj regiji. Grga, Ðurica; Dželetovic, Bojan; živković, Slavoljub; Kršljak, Elena // Serbian Dental Journal / StomatoloÅ¡ki Glasnik Srbije;Sep2010, Vol. 57 Issue 3, p146 

    No abstract available.

  • Laser Doppler Perfusion Imaging of Skin Blood Flow Using Red and Near-Infrared Sources. Abbot, Neil C.; Ferrell, William R.; Lockhart, John C.; Lowe, J. Graham // Journal of Investigative Dermatology;Dec96, Vol. 107 Issue 6, p882 

    At present, scanning laser Doppler imaging uses a 633-nm helium-neon laser (RED) as the only light source, but this restricts its ability to measure blood flow (i) at darkly pigmented skin and (ii) from deeper or subdermal structures. Because near-infrared (NIR) light is known to penetrate...

  • Occlusion of the brachiocephalic trunk. Thalhammer, Christoph; Aschwanden, Markus; Jäger, Kurt A // Vascular Medicine;2004, Vol. 9 Issue 4, p313 

    The article cites a study on the occlusion of the brachiocephalic trunk. The subject of the study was a 78-year-old woman who came in for evaluation of carotid bruits. At the time she was an inpatient at the department of general surgery due to a rupture of the achilles tendon. Researchers...

  • Venous Hypertensive Microangiopathy in Relation to Clinical Severity and Effect of Elastic Compression. Christopoulos, D. C.; Nicolaides, A. N.; Belcaro, G.; Kalodiki, E. // Journal of Dermatologic Surgery & Oncology;Oct91, Vol. 17 Issue 10, p809 

    Arterial inflow in mL/minute and perimalleolar skin blood flow were measured with venous occlusion air-plethysmography and laser-Doppler flowmetry in 20 normal limbs, 40 limbs with uncomplicated primary varicose veins, 32 limbs with primary varicose venis and skin changes, and 36 limbs with...

  • LASER DOPPLER FLOWMETRY (LDF) & POST-OCCLUSIVE SKIN REACTIVE HYPERAEMIA FOR THE ASSESSMENT OF MICROVASCULAR FUNCTION -- EFFECT OF GENDER, MENSTRUAL CYCLE & AGE. G. R., Aida Hanum; G. B., Tee; A. R., Abd Rashid; H., Ahmad Sukari; W., Abd Rahim // Malaysian Journal of Medical Sciences;Jan2008 Supplement, p120 

    Introduction: Post-occlusive skin reactive hyperaemia (PORH) is increased skin blood flow following release of a brief arterial occlusion. PORH and laser Doppler flowmetry (LDF) is used as a model to assess microvascular function. Objective: to assess the effects of estrogen changes in the...

  • POST-OCCLUSIVE REACTIVE HYPEREMIA MODEL TO ASSESS MICROVASCULAR FUNCTION -- A DESCRIPTIVE STUDY. A., Haswati; W., Abdul Rahim; H., Ahmad Sukari; A. R., Abdul Rashid; G. R., Aida Hanum // Malaysian Journal of Medical Sciences;Jan2006 Supplement, Vol. 13, p189 

    PURPOSE : The process of post occlusive reactive hyperaemia [PORH] using laser doppler fluximetry [LDF] is a non invasive method to assess microvascular function. This study describes the process and results obtained in 178 healthy subjects. METHOD : This prospective study involved 72 male and...

  • Simultaneous Changes in Leg Arterial Pulsatile Blood Flow and Toe Laser-Doppler Perfusion Accompanying Graded Thigh Compression. Mayrovitz, Harvey N. // Vascular Surgery;Jul/Aug1998, Vol. 32 Issue 4, p329 

    Previous findings showed that regional ankle cuff compression and below-knee compression bandaging cause significant decreases in skin blood perfusion distal to the compressed regions. Contrastingly, with compression bandaging, as is commonly used in the treatment of venous ulcers and other...

  • A laser Doppler flowmeter using variable coherence to effect depth discrimination. Dougherty, G. // Review of Scientific Instruments;May92, Vol. 63 Issue 5, p3220 

    A novel means of investigating blood flow at different depths within the skin is described. By varying the coherence length of the diode laser source, the depth of the sampling volume over which Doppler signals are received could be controlled in a simple model system. The instrument has a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics