TITLE

PRELIMINARY OBSERVATIONS ON THE ROLE OF MONOAMINE OXIDASE INHIBITORS IN THE THERAPY OF PERIPHERAL ARTERIAL DISEASE

AUTHOR(S)
Samuels, Saul S.; Shaftel, Herbert E.
PUB. DATE
February 1960
SOURCE
Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p90
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Exploratory studies of the role of monoamine oxidase inhibition with Nardil in patients with peripheral circulatory disturbances are described. This drug is effective in relieving the pain of claudication, although confirmatory increase in peripheral blood flow was not observed (during the period of study) unless supplemental vasodilation was included. Vasomotor disturbances, however, were virtually completely eliminated by the drug. It is hoped that continued study will elaborate the essential mechanisms for this drug and, thereby, help to define its exact therapeutic role in the management of peripheral arterial disease.
ACCESSION #
16365492

 

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