TITLE

MONOAMINE OXIDASE INHIBITORS AND ANGINA PECTORIS

AUTHOR(S)
Winsor, Travis; Zarco, Pedro
PUB. DATE
February 1960
SOURCE
Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p67
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Four monoamine oxidase (MAO) inhibitors, all hydrazine analogs of Marsilid, were studied and it was found that anginal pain was relieved by all of these agents. The most serious side effect was postural hypotension which was most common in patients receiving chlorothiazide and in those with a previous myocardial infarct. Other side effects were mild. It is felt that an exciting new field of study has opened up and that intensive investigation of the MAO inhibitors may lead to a better understanding of the nature of angina pectoris.
ACCESSION #
16365471

 

Related Articles

  • MONOAMINE OXIDASE INHIBITORS IN THE TREATMENT OF ANGINA PECTORIS. Russek, Henry I. // Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p76 

    Drugs that are effective in the control of anxiety and depression in patients with angina pectoris are important adjuvants in therapy. Tranquilizers and sedatives have been found to reduce nitroglycerin requirements and to increase the capacity for exercise in patients with anxiety symptoms. The...

  • INDICATIONS, CONTRAINDICATIONS AND TREATMENT WITH MONOAMINE OXIDASE INHIBITING ANTIDEPRESSANT DRUGS. Sainz, Anthony // Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p94 

    The monoamine oxidase inhibitors, based on modifications of hydrazine, have been defined, and their pharmacologic position, e.g., as antidepressants rather than stimulants, analeptics, etc., has been specifically clarified and documented. An operational classification and definition of the...

  • Neuroprotective effect of rasagiline, a monoamine oxidase-B inhibitor, on spontaneous cell degeneration in a rat model. Eliash, S.; Shteter, N.; Eilam, R. // Journal of Neural Transmission;Aug2005, Vol. 112 Issue 8, p991 

    Spontaneously hypertensive rats (SHR) pathologically elevate blood pressure with age. This elevation is accompanied by specific neuronal degeneration in the hypothalamus and enlargement of the lateral ventricles. The aim of this study was to assess the neuroprotective effect of the monoamine...

  • CORONARY ARTERY DISEASE: THE USE OF MONOAMINE OXIDASE INHIBITORS IN THE TREATMENT OF THE ANGINAL SYNDROME. Friedgood, Charles E. // Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p84 

    1. A total of 26 patients with anginal syndrome were treated with Nardil for the relief of pain. 2. Twenty-one patients showed good or excellent response to the daily oral dose of 45 mg. 3. Side effects presented a minor problem in only 1 patient. There appears to be a relation between larger...

  • PERIPHERAL VENOUS PLATELET AGGREGATES IN PATIENTS WITH UNSTABLE ANGINA PECTORIS AND ACUTE MYOCARDIAL INFARCTION. Guyton, John R.; Willerson, James T. // Angiology;Oct1977, Vol. 28 Issue 10, p695 

    In vivo peripheral venous platelet aggregates (PVPA) have been demonstrated in patients with myocardial infarction (MI), transient cerebral ischemic attacks (TIAs), and acute arterial insufficiency by the platelet count ratio (PCR) method. But PVPA determination have not been reported in...

  • Current Management of Unstable Angina. Kaindl, F.; Pachinger, O.; Zilcher, H. // Angiology;Feb1980, Vol. 31 Issue 2, p126 

    The article discusses ways for the management of unstable angina. In dealing with unstable angina, the first problem is the terminology: The lack of clear objective criteria for a precise diagnosis of this syndrome is the major reason for the tremendous differences in mortality rates, infarction...

  • propranolol.  // Davis's Drug Guide for Nurses, 10th edition;2007, p1001 

    The article offers information on propranolol, an antianginal, antiarrhythmic, antihypertensive drug and vascular head suppressant. The drug is used in the management of hypertension, angina pectoris, arrhythmias and myocardial infarction. Some of the adverse reaction or side effects of the drug...

  • PRELIMINARY OBSERVATIONS ON THE ROLE OF MONOAMINE OXIDASE INHIBITORS IN THE THERAPY OF PERIPHERAL ARTERIAL DISEASE. Samuels, Saul S.; Shaftel, Herbert E. // Angiology;Feb1960 Part 2, Vol. 11 Issue 1, p90 

    Exploratory studies of the role of monoamine oxidase inhibition with Nardil in patients with peripheral circulatory disturbances are described. This drug is effective in relieving the pain of claudication, although confirmatory increase in peripheral blood flow was not observed (during the...

  • Determinants of Long-Term Mortality in Patients With Type B Acute Aortic Dissection. Sakakura, Kenichi; Kubo, Norifumi; Ako, Junya; Fujiwara, Naoki; Funayama, Hiroshi; Ikeda, Nahoko; Nakamura, Tomohiro; Sugawara, Yoshitaka; Yasu, Takanori; Kawakami, Masanobu; Momomura, Shin-ichi // American Journal of Hypertension;Apr2009, Vol. 22 Issue 4, p371 

    BackgroundType B acute aortic dissection (AAD) carries a high short- and midterm mortality rate; however, knowledge related to long-term outcome is largely incomplete. The objective of this study was to identify long-term predictors including antihypertensive medications in type B AAD.MethodsWe...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics