TITLE

STUDIES OF MYOCARDIAL CONTRACTILE PROTEINS AND MITOCHONDRIAL SUCCINATE DEHYDROGENASE DURING PARTIAL HEART-LUNG BYPASS

AUTHOR(S)
Cho, Young W.; Zanuttini, Domenico; Galletti, Pierre M.; Watson, C. Thomas
PUB. DATE
August 1965
SOURCE
Angiology;Aug1965, Vol. 16 Issue 8, p443
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Myocardial actin-myosin systems, cardiac mitochondrial succinate dehydrogenase activity and the adenosine nucleotides-creatine phosphate levels of the heart muscle have been studied in groups of dogs after isovolemic 3-hour partial heart-lung bypass procedures (at the flow rate of about half of the cardiac output rate) and after 3-hour bypass and 4-week recovery period, and these results have been compared with the findings in the control group. Cardiac contractile proteins remain intact; however, the succinate dehydrogenase activity is decreased immediately after the bypass, but this change is reversible. The myocardial energy-rich phosphate levels are at their constant level.
ACCESSION #
16365254

 

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