Shaftel, Herbert E.; Samuels, Saul S.; Padernacht, Elias; Halpern, Alfred
October 1960
Angiology;Oct1960 Part 2, Vol. 11 Issue 5, p480
Academic Journal
1. A survey throughout the United States demonstrated the frequency of occurrence of vascular accidents associated with bowel function. 2. A study of the effects of therapeutic agents in causing drug-induced constipation revealed this to be an important factor which deserves serious attention by the clinician. 3. The administration of the neuroperistaltic constipation corrective, Senokot, successfully corrected the constipation when encountered, and when administered concomitantly with the therapeutic agent it prevented its onset. There was no interference with the pharmacodynamic activity of the principal therapeutic agent by this procedure. 4. The administration of this agent together with drugs capable of causing constipation is recommended in order to reduce the stress to the circulatory system arising from the straining efforts associated with bowel function.


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