TITLE

A PLETHYSMOGRAPHIC STUDY OF THE EFFECT OF TETRANICOTINOYLFRUCTOSE (BRADILAN) ON DIGITAL BLOOD FLOW IN PRIMARY AND SECONDARY RAYNAUD'S PHENOMENON

AUTHOR(S)
Antcliff, A. C.; Bouhoutsos, John; Martin, Peter; Morris, Tom
PUB. DATE
May 1974
SOURCE
Angiology;May1974, Vol. 25 Issue 5, p312
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A plethysmographic study of the effect of TNF on digital blood flow was made in normal subjects, in patients with primary Raynaud's phenomenon and in patients with scleroderma. It significantly increased resting und post-is-chaemic blood flow in all three groups of subjects and resting blood flow in normal individuals and those with primary Raynaud's phenomenon. It also greatly increased resting blood flow in 5 patients with scleroderma but this is not statistically significant. These effects were produced with only a minimal fall in systolic blood pressure and the only side effect was occasional flushing of the face.
ACCESSION #
16360126

 

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