PERHEXILINE MALEATE, A NEW ANTI-ANGINAL DRUG, EVALUATED BY "MODIFIED DOUBLE BLIND DOUBLE CROSS OVER STUDY"
- Antianginal combination reduces cardiac events, but causes headaches. // Modern Medicine;Aug97, Vol. 65 Issue 8, p53
Presents an abstract of `Effect of Transdermal Nitroglycerin or N-acetylcysteine, or Both, in the Long-Term Treatment of Unstable Angina Pectoris,' by D. Ardissino, P.A. Merlini, et al from the `Journal of the American College of Cardiology' dated April 1997.
- Selection and dosing of nitrates to avoid tolerance during sustained antianginal therapy. Shaw, Sonia V.; Hunter, Walter J.; Shirer, Alyson E. // Formulary;Jul99, Vol. 34 Issue 7, p590
Discusses the selection and dosing of nitrates to avoid tolerance during sustained antianginal therapy. Pharmacology; Pharmacokinetics; Nitrate tolerance; Dosage, formulations and pricing; Oral agents; Action; Safety; Regimen selection. INSET: Nitrate therapy: Guidance for formulary decision...
- Challenges with Nitrate Therapy and Nitrate Tolerance: Prevalence, Prevention, and Clinical Relevance. Thadani, Udho // American Journal of Cardiovascular Drugs;Aug2014, Vol. 14 Issue 4, p287
Nitrate therapy has been an effective treatment for ischemic heart disease for over 100 years. The anti-ischemic and exercise-promoting benefits of sublingually administered nitrates are well established. Nitroglycerin is indicated for the relief of an established attack of angina and for...
- amlodipine. Peters, Michael // BMA A-Z Family Medical Encyclopedia;2004, p36
An encyclopedia entry for "amlodipine" is presented. Amlodipine is a calcium channel blocker administered to prevent angina and treat hypertension. Adverse events associated with amlodipine intake include headaches and dizziness.
- A Randomized, Double-Blind, Placebo-Controlled, Crossover, Dose-Ranging Multicenter Study to Determine the Effect of Sublingual Nitroglycerin Spray on Exercise Capacity in Patients with Chronic Stable Angina. Thadani, Udho; Wittig, Thomas // Clinical Medicine Insights: Cardiology;2012, Issue 6, p87
Background: Sublingual nitroglycerin increases exercise duration in patients with stable angina. Brief results from this study were published previously in German. Here, we more fully describe the study methodology, patient characteristics, and detailed results. Methods: This double-blind,...
- Single crystalline phase photochemical properties and structure of a new biindenylidenedione bearing cyclohexyl groups. Song, Zhi-Yi; Xu, Li-Li; Han, Jie; Yu-Xin; Meng, Ji-Ben // Research on Chemical Intermediates;2004, Vol. 30 Issue 4/5, p537
The crystal structure of the title compound, named [2,2â€²-bi-1H-indene]-1,1â€²-dione-3,3â€²-dihydroxyl-3,3â€²-dicyclohexyl (I), has been determined by X-ray crystallographic techniques. The photoinduced radical and photochromic behavior of I has also been investigated in the...
- Efficacy of Ivabradine in Combination with Beta-Blocker Versus Uptitration of Beta-Blocker in Patients with Stable Angina. Amosova, E.; Andrejev, E.; Zaderey, I.; Rudenko, U.; Ceconi, C.; Ferrari, R. // Cardiovascular Drugs & Therapy;Dec2011, Vol. 25 Issue 6, p531
Purpose: The antianginal and anti-ischemic efficacy of the selective I inhibitor ivabradine is established in patients with stable angina in monotherapy and in combination with other antianginals, including beta-blocker. This pilot study compared the antianginal and anti-ischemic efficacy and...
- Anleitungen und Methodik zur klinischen PrÃ¼fung von Arzneimitteln fÃ¼r die Therapie der stabilen Angina pectoris. Wink, Konrad // Drug Research / Arzneimittel-Forschung (Editio Cantor Verlag fur;Dec2003, Vol. 53 Issue 12, p864
Zum Nachweis der antiang inÃ¶sen Wirksamkeit einer medikamentÃ¶sen Therapie bel stabiler Angina pectoris ist die Beachtung von bestimmten Kriterien bei der Planung und DurchfÃ¼ihrung von kilnischen Arzneimittelstudien notwendig. Diese umfassen das Studiendesign, die Randomisierung,...
- Comparison of Carvedilol and Metoprolol in Stable Angina. Sadovsky, Richard // American Family Physician;6/1/1999, Vol. 59 Issue 11, p3183
Presents a summary of the article `Comparison of Safety and Efficacy of Carvedilol and Metoprolol in Stable Angina Pectoris,' by R. Van der Does, et al., published in the March 1, 1999 issue of the `American Journal of Cardiology.'