TITLE

PRELIMINARY STUDIES ON IN VITRO AND IN VIVO EFFECTS OF 50% HYPAQUE ON COAGULATION IN MAN

AUTHOR(S)
Chandra, Ramesh; Abraham, Jacob
PUB. DATE
April 1973
SOURCE
Angiology;Apr1973, Vol. 24 Issue 4, p199
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A preliminary study of in Vitro and in Vivo changes in the various factors of coagulation by 50% Hypaque in man is reported. Significant inhibition of all the stages of clotting and increased fibrinolytic activity were demonstrated by various special laboratory tests. Persistence of such coagulation defects after pancerebral angiography was observed even after 24 hours. It is suggested that binding of factors of coagulation with the contrast medium may be the underlying cause. A gross reduction of Serum Calcium in an in vitro Blood-Hypaque mixture of a blood sample drawn from a patient prior to angiography, compared with a venous blood sample may serve as an index for possible adverse reaction. It indicates not only the extent of alteration in Calcium level but also reflects indirectly the reduction in serum protein and the factors of coagulation.
ACCESSION #
16359914

 

Related Articles

  • Transarterial Embolization of Giant Liver Hemangiomas Associated with Kasabach-Merritt Syndrome: A Case Report. Malagari, K.; Alexopoulou, E.; Dourakis, S.; Kelekis, A.; Hatzimichail, K.; Sissopoulos, A.; Delis, S.; Letsou, D.; Kelekis, D. // Acta Radiologica;Aug2007, Vol. 48 Issue 6, p608 

    Of 22 patients with symptomatic giant liver hemangiomas referred for embolization, two females (52 and 74 years) had Kasabach-Merritt syndrome (KMS). Hematocrit values were observed to be 33% and 29%, platelets 4000 and 5400/mm3, and fibrinogen 98 and 77 mg/dl, respectively. Lesion diameters...

  • Tromboelastografía: nuevos conceptos en la fisiología de la hemostasia y su correlación con la coagulopatía asociada al trauma. Galvez, Kenny; Cortes, Claudia // Colombian Journal of Anesthesiology / Revista Colombiana de Anes;ago-oct2012, Vol. 40 Issue 3, p224 

    Initial interpretation of the process of coagulation refers to two pathways: (1) the extrinsic pathway, consisting of tissue factor (TF) and factor VII, and (2) the intrinsic pathway, in which factors XII, XI, IX, VIII and V are involved. Currently, this concept has changed and it is accepted...

  • The Involvement of Blood Coagulation Factor XIII in Fibrinolysis and Thrombosis. Muszbek, L.; Bagoly, Z.; Bereczky, Z.; Katona, É. // Cardiovascular & Hematological Agents in Medicinal Chemistry;2008, Vol. 6 Issue 3, p190 

    It has been known for a long time that blood coagulation factor XIII (FXIII) is essential for maintaining haemostasis, its deficiency leads to severe bleeding complication. Biochemical studies have revealed that FXIII is a key regulator of fibrinolysis and, in addition to its role in...

  • Recent advances in clot biology and assessment of clotting. Hedner, Ulla; Ezban, Mirella // Trauma;Oct2008, Vol. 10 Issue 4, p261 

    Since the first description of the haemostatic process by Morawitz in 1904, knowledge about the haemostasis mechanism has undergone substantial modifications. Increasing knowledge of enzymology, purification and characterisation of coagulation proteins led to the introduction of the waterfall or...

  • The use of recombinant activated coagulation factor VII for spine surgery. Weiskopf, Richard B. // European Spine Journal;Feb2004 Supplement 1, Vol. 13, pS83 

    This article focuses on our current understanding of the role of activated coagulation factor VII (FVIIa) in coagulation, the current evidence regarding the efficacy and safety of recombinant FVIIa (rFVIIa), and thoughts regarding the use of rFVIIa in spine surgery. rFVIIa is approved in many...

  • Bacteria Cut Out the Middleman in Activating Clotting Cascade. Breindl, Anette // BioWorld Today;11/6/2008, Vol. 19 Issue 217, p1 

    The article discusses research being done on the influence of bacteria on blood clotting. It references a study by James Boedicker and colleagues, published win the November 2, 2008 online edition of "Nature Chemical Biology." The study tested over 50 possible combinations of factors that...

  • KaraciÄŸer hastalıklarında pıhtılaÅŸma-tromboz mekanizmasına neler oluyor? Tiraje Celkan, Tülin // Turkish Pediatrics Archive / Turk Pediatri Arsivi;Jun2013, Vol. 48 Issue 2, p94 

    Children with liver disease present complex and varied acquired coagulation abnormalities. Liver is the place where clotting factors are produced as well as inhibitors of coagulation and fibrinolytic system components. Although 75-85% of patients with liver disease show abnormal laboratory...

  • A Mathematical Model of the Background State of the Blood Coagulation System. Obraztsov, I. F.; Kardakov, D. V.; Kogan, A. E.; Khanin, M. A. // Doklady Biochemistry & Biophysics;Jan/Feb2001, Vol. 376 Issue 1-6, p10 

    Presents a study which examined the background state of the blood coagulation system using the method of mathematical simulation. Description of a mathematical model of blood coagulation; Role of tissue factor in the coagulation system; Effect of deficiency of factors II, V, VII, VIII, IX and X...

  • Fibrinogen: A Predictor of Vascular Disease. Kakafika, A. I.; Liberopoulos, E. N.; Mikhailidis, D. P. // Current Pharmaceutical Design;Jun2007, Vol. 13 Issue 16, p1647 

    Raised plasma fibrinogen levels are associated with an increased risk of vascular events. This may be mediated by adverse effects of fibrinogen on plasma viscosity, coagulation, platelet activity, inflammation and atherogenesis. However, there is as yet no drug that specifically lowers plasma...

Share

Read the Article

Courtesy of VIRGINIA BEACH PUBLIC LIBRARY AND SYSTEM

Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics