TITLE

THE EFFECTS OF RESERPINE ON ATRIOVENTRICULAR CONDUCTION IN MAN

AUTHOR(S)
Gould, Lawrence; Reddy, C. V. R.; Gomprecht, Robert F.
PUB. DATE
May 1975
SOURCE
Angiology;May1975, Vol. 26 Issue 5, p377
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
His bundle electrograms were obtained in 14 patients before and 30 minutes after the intravenous administration of reserpine. Nine patients received 1.0 mg of reserpine while 5 patients were given 0.5 mg. Reserpine did not alter the HQ or HS intervals. However, there were variable effects on the PA and AH intervals. These results can be explained by the interplay of two factors, norepinephrine release and a direct depressant action of the drug. Conduction through the AV node will be improved or delayed depending on which factor is dominant.
ACCESSION #
16359789

 

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