Wheeler, H. Brownell; O'Donnell, Joseph A.; Anderson, Frederick A.; Penney, Bill C.; Peura, Robert A.; Benedict Jr., Carl
February 1975
Angiology;Feb1975, Vol. 26 Issue 2, p199
Academic Journal
Venous thromboembolic disease exists on a clinical spectrum ranging from insignificant clots in the calf veins to fatal pulmonary emboli. The process usually begins in the calf veins, where clots are common, but are unlikely to he associated with any major complications. Thrombosis in the popliteal, femoral, or iliac veins is much less common, but may lead to death from pulmonary embolism or result in long-term disability from the postphlebitic syndrome. Early diagnosis and prompt treatment of these main vessel clots is essential in order to reduce the major complications of thromboembolic disease. For prompt and accurate bedside diagnosis of main vessel thrombosis, occlusive impedance phlebography has proved most useful. This procedure measures the venous volume response to temporary venous outflow obstruction. It bas been employed in 720 patients with a variety of medical conditions. The method proved 98% accurate in distinguishing main vessel clot from a normal venous system (146�149 consecutive phlebograms). It usually failed to detect isolated calf vein clots or old thrombophlebitis which had recanalized or developed abundant collateral circulation.


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