Evaluation of Quinidine Short and Long-Acting in Control of Arrhythmias

Coodley, Eugene; Pugash, Neil; Toppo, Frank
September 1984
Angiology;Sep1984, Vol. 35 Issue 9, p581
Academic Journal
Twenty-one patients with arrhythmias responsive to quinidine were studied both with regard to consistency of response as determined by repeat Holter Monitoring and in half of these patients a comparison of short and long-acting quinidine was made. Holter Monitoring demonstrated greater than 60% reduction of ectopic activity in all but one patient and reproducibility varied by less than 10% in nineteen of twenty-one patients. Nine of eleven patients showed the same response to long-acting quinidine as compared to short-acting. Eight of nine patients having significant numbers of ectopic pairs showed a significant reduction with quinidine therapy, both short-acting and long-acting.


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