Clark, Thomas E.; Cross, Charles J.
May 1965
Angiology;May1965, Vol. 16 Issue 5, p238
Academic Journal
The clinical effectiveness of a well known sedative, butabarbital, alone and in combination with hydrochlorothiazide and/or reserpine in the treatment of hypertensive heart disease has been evaluated. A clinical impression has been obtained that these preparations are effective agents in a significant number of patients. The results show a generally superior response both in antianxiety and antihypertensive effects. Although the role of the barbiturate has not been scientifically established, there is a clinical impression that it adds to the therapeutic usefulness of an antihypertensive preparation. The combination appears to gave a latitude of therapy for the various grades of essential hypertension which would not be possible with a single preparation.


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