Nakamura, Shozo; Sasaki, Ko; Takezawa, Yoshiaki; Yoshida, Gen; Sato, Takashi
July 1974
Angiology;Jul/Aug1974, Vol. 25 Issue 7, p484
Academic Journal
An improved method is presented for the determination of the intrahepatic shunted blood flow. D-Galactose-1-C14 and T-1824 dye were continuously infused at a constant rate into the pulmonary artery. Per cent intrahepatic shunt was calculated from the radioactivities and dye concentrations of the arterial and the hepatic venous blood. Per cent intrahepatic shunt of 4 controls and 2 patients with acute viral hepatitis was 8–18. Twelve patients with chronic hepatitis showed 6–29 per cent of intrahepatic shunt with an average of 20 per cent, and 16 patients with hepatic cirrhosis showed 23–60 per cent of shunt with an average of 35 per cent. Thus, per cent intrahepatic shunt increased slightly in chronic hepatitis and markedly in hepatic cirrhosis. The range of overlap of per cent intrahepatic shunt between hepatic cirrhosis and chronic hepatitis was narrower by the present continuous infusion method than by the previous rapid injection method. There were statistically significant correlations between the per cent intrahepatic shunt and the per cent of interstitial tissue and between the per cent intrahepatic shunt and the wedged hepatic venous pressure.


Related Articles

  • Peculiarities of Compensatory Reactions of Hepatic Vessels during Experimental Coarctation of Aorta. S. Shormanov; S. Kulikov // Bulletin of Experimental Biology & Medicine;Jan2009, Vol. 147 Issue 1, p104 

    Morphometric and histological methods were employed to study structural changes of hepatic vessels in dogs with compensated coarctation. Simulation of this conditions in animals decreased vascular tone in the inflow and outflow beds of hepatic blood supply and led to the development of atrophy...

  • Liver blood flow during cardiac surgery. Chetty, Govind; Sharpe, David A.C.; Nandi, Jay; Butler, Stephen J.; Mitchell, Ian M. // Perfusion;May2004, Vol. 19 Issue 3, p153 

    Objective: Impairment of liver blood flow and, therefore, potentially liver function, has important short-term consequences because of the liver's key metabolic importance and role in drug metabolism. The objective of this study was to quantify the effect of cardiac surgery on liver blood flow...

  • HEPATIC FALCIFORM ARTERY. Baba, Y.; Miyazono, N.; Ueno, K.; Kanetsuki, I.; Nishi, H.; Inoue, H.; Nakajo, M. // Acta Radiologica;Jul2000, Vol. 41 Issue 4, p329 

    AbstractPurpose: To determine the frequency of hepatic falciform artery (HFA) occurrence on celiac or hepatic angiograms and elucidate the anatomy and clinical importance. Material and Methods: Among 1,250 patients who underwent celiac or hepatic arteriography, we encountered 25 patients (2%)...

  • Histologic changes mimicking biliary disease in liver biopsies with venous outflow impairment. Kakar, Sanjay; Batts, Kenneth P.; Poterucha, John J.; Burgart, Lawrence J. // Modern Pathology;Jul2004, Vol. 17 Issue 7, p874 

    Impairment of venous outflow from the liver manifests as zone 3 sinusoidal dilatation and congestion (SDC) in liver biopsy. The spectrum of histologic changes in portal tracts has not been described. We studied liver biopsies from 34 patients with a confirmed diagnosis of venous outflow...

  • The Estimation of Hepatic Blood Flow with Indocyanine Green: Comparison between the Continuous Infusion and Single Injection Methods. Villeneuve, J. P.; Marleau, D.; Huet, P. M. // American Journal of Gastroenterology;Apr1982, Vol. 77 Issue 4, p233 

    We compared the estimation of hepatic blood flow obtained using a continuous infusion of indocyanine green with that obtained after a single intravenous injection of indocyanine green in 35 patients with liver disease. There was no significant difference in the values of hepatic blood flow...

  • Effects of acoustic nonlinearity and blood flow cooling during HIFU treatment. Solovchuk, Maxim A.; Sheu, Tony W. H.; Thiriet, Marc // AIP Conference Proceedings;Nov2012, Vol. 1503 Issue 1, p83 

    The present study is aimed at predicting liver tumor temperature during a high-intensity focused ultrasound (HIFU) thermal ablation in a patient-specific liver geometry. The model comprises the nonlinear Westervelt equation and bioheat equations in liver and blood vessel. The nonlinear...

  • MEASUREMENT OF INTRAHEPATIC SHUNTED BLOOD FLOW BY MEANS OF D-GALACTOSE-1-C14 IN EXPERIMENTAL HEPATIC INJURIES. Nakamura, Takashi; Nakamura, Shozo; Onodera, Atsushi; Aikawa, Tatsuya; Kera, Kiyoshi // Angiology;Sep1970, Vol. 21 Issue 8, p493 

    D-galactose-1-C14 was injected into the mesenteric vein or into the hepatic artery of rats, and per cent intrahepatic shunt was calculated from the radioactivity of the resected liver and that of the injected solution. When the D-galactose-1-C14 solution was injected into the mesenteric vein,...

  • Regulation of hepatic blood flow: The hepatic arterial buffer response revisited. Eipel, Christian; Abshagen, Kerstin; Vollmar, Brigitte // Annals of Gastroenterology & Hepatology;2011, Vol. 9 Issue 94, p6046 

    The interest in the liver dates back to ancient times when it was considered to be the seat of life processes. The liver is indeed essential to life, not only due to its complex functions in biosynthesis, metabolism and clearance, but also its dramatic role as the blood volume reservoir. Among...

  • Effect of Famotidine on Hepatic Hemodynamics and Peptic Ulcer. Ohnishi, Kunihiko; Saito, Masayuki; Nomura, Fumio; Okuda, Kunio; Suzuki, Naondo; Ohtsuki, Toshio; Goto, Nobuaki; Takashi, Motohide // American Journal of Gastroenterology;May1987, Vol. 82 Issue 5, p415 

    The acute effects of histamine H2 receptor antagonist, famotidine, on hepatic hemodynamics were studied in six normal volunteers and eight patients with chronic liver disease, and its chronic effects on peptic ulcer, portal hemodynamics, and hepatic function were studied in 20 patients with...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics