TITLE

ANGIOLOGIC ASSESSMENT OF THE HEMODYNAMIC EFFECTS OF SUSTAINED RELEASE NITROGLYCERIN IN PATIENTS WITH ANGINA PECTORIS

AUTHOR(S)
Thompson, Eugene J.; Glass, Paul; Torres, Crisanto; Arora, Jodh; Piccone Jr., Vincent A.
PUB. DATE
September 1973
SOURCE
Angiology;Sep1973, Vol. 24 Issue 8, p508
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
In summary, the hemodynamic effects of a sustained-release oral nitroglycerin preparation were studied by means of a carefully controlled exercise protocol in a group of 20 adult males with stable angina pectoris. Statistically significant increases in cardiac index, stroke index, and &Vdot;O2 max were observed after drug administration. A similarly significant decrease in systemic vascular resistance was also seen. The observed improvements were sustained for periods up to four hours and are interpreted as direct consequences of the sustained-release nitroglycerin.
ACCESSION #
16358032

 

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