Trimmer, Ralph W.; Olwin, John H.
December 1956
Angiology;Dec1956, Vol. 7 Issue 6, p537
Academic Journal
In eight apparently healthy mongrel dogs there was no significant variation in the erythrocyte sedimentation rate during and following the administration of Dicumarol in doses which produced prothrombin levels comparable to those produced therapeutically in human beings. In one dog there was an increase in the erythrocyte sedimentation rate due to a skin infection. In another dog, there was also an increase in the ESR without any known cause. The results of the study indicate that Dicumarol does not uniformly affect the sedimentation rate in dogs, providing further support for the position held by some authors that Dicumarol does not invalidate the use of the test in the study and treatment of patients with myocardial infarction.


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