PANEL DISCUSSION FOLLOWING THE SURVEY BY DR. BERENSON
- A purified catalytically competent spliceosome. Konarska, Maria M. // Nature Structural & Molecular Biology;Mar2008, Vol. 15 Issue 3, p222
The article focuses on the refinement of the spliceosome's composition. It discusses the significance of purification of the splicing complex C of spliceosome in eradicating serious obstruction in experimental analysis due to its complexity. It mentions that through purification, accomplish the...
- Detecting Mutually Exclusive Interactions in Protein-Protein Interaction Maps. Sánchez Claros, Carmen; Tramontano, Anna // PLoS ONE;Jun2012, Vol. 7 Issue 6, p1
Comprehensive protein interaction maps can complement genetic and biochemical experiments and allow the formulation of new hypotheses to be tested in the system of interest. The computational analysis of the maps may help to focus on interesting cases and thereby to appropriately prioritize the...
- Cell adhesion molecules. Murray, Paul; Frampton, G // BMJ: British Medical Journal (International Edition);08/07/99, Vol. 319 Issue 7206, p332
Editorial. Focuses on cell adhesion molecules. Groups of cell adhesion molecules; Roles in the physiological processes and disease states; Usefulness in diagnostics and therapeutics.
- Materials science: At a stretch. Daw, Rosamund // Nature;10/13/2005, Vol. 437 Issue 7061, p961
Examines the polymer based on the elastic protein that enables fleas to perform their extraordinary jumping feats. Effect of the photochemical reaction on peptide; Production of a polymer by first cloning part of a Drosophila fruitfly gene and expressing it in Scherzi coli bacteria; Mechanical...
- Signal transduction by the a6ÃŸ4 integrin: distinct ÃŸ4 subunit sites mediate recruitment of Shc/Grb2 and association with the cytoskeleton of hemidesmosomes. Mainiero, F.; Pepe, A.; Wary, K. K.; Spinardi, L.; Mohammadi, M.; Schlessinger, J.; Giancotti, F. G. // EMBO Journal;10/15/2000, Vol. 19 Issue 20, p5585
Discusses facts about signal transduction by the Î±6Î²4 integrin. Role of the Î±6Î²4 integrin as a major receptor for the basement membrane component laminin 5; Activation of mitogen-activated protein kinase cascades; Formation of hemidesmosome-like adhesions.
- A Comprehensive Analysis of the Structure-Function Relationship in Proteins Based on Local Structure Similarity. Hvidsten, Torgeir R.; Lægreid, Astrid; Kryshtafovych, Andriy; Andersson, Gunnar; Fidelis, Krzysztof; Komorowski, Jan // PLoS ONE;2009, Vol. 4 Issue 7, p1
Background: Sequence similarity to characterized proteins provides testable functional hypotheses for less than 50% of the proteins identified by genome sequencing projects. With structural genomics it is believed that structural similarities may give functional hypotheses for many of the...
- Chemical analysis of osmium tetroxide staining in adipose tissue using imaging ToF-SIMS. Belazi, Dalila; Solé-Domènech, Santiago; Johansson, Björn; Schalling, Martin; Sjövall, Peter // Histochemistry & Cell Biology;Jul2009, Vol. 132 Issue 1, p105
Osmium tetroxide (OsO4) is a commonly used stain for unsaturated lipids in electron and optical microscopy of cells and tissues. In this work, the localization of osmium oxide and specific lipids was independently monitored in mouse adipose tissue by using time-of-flight secondary ion mass...
- CELL SIGNALLING: The MIDAS touch. Smallridge, Rachel // Nature Reviews Molecular Cell Biology;May2002, Vol. 3 Issue 5, p313
Discusses research being done on integrin Î±VÎ²3. Reference to a study by J. P. Xiong et al., published in a 2002 issue of the journal "Science"; Components of integrins; Nature of an Î±A domain.
- Heterophilic Adhesion. Vohr, Hans-Werner // Encyclopedic Reference of Immunotoxicology;2005, p285
A definition of the term "heterophilic adhesion" is presented. It refers to adhesion between two undefined cell types mediated by different adhesion molecules.