Villamil, Mario Fernandez; Beheran, Hugo
April 1956
Angiology;Apr1956, Vol. 7 Issue 2, p179
Academic Journal
Intra-arterial trypsin with procaine and an antihistaminic was used in the management of acute phlebothrombosis, thrombophlebitis and its sequelae. In phlebothrombosis, pain and edema were quickly alleviated, the course of the disease being shortened and the sequelae either avoided or lessened. In one case of primary thrombophlebitis with an allergic background an anaphylactic-like local reaction occurred which made it necessary to stop the treatment. As a treatment of thrombophlebitic sequelae trypsin showed poor results in postphlebitic edema, while it was moderately effective in dermatosclerosis, and highly effective in postphlebitic ulcers.


Related Articles

  • Deep Venous Thrombosis of the Upper Extremity Five Years Experience at a University Hospital. Painter, Thomas D.; Karpf, Michael // Angiology;Nov1984, Vol. 35 Issue 11, p743 

    All patients with deep vein thrombosis of the arm seen at one University Hospital over a 5 year period were reviewed. The 17 cases could be divided into distinct patient groups. The first group (primary thrombosis) consisted of 7 patients primarily healthy young males (mean age 23) who had...

  • Unilateral Extremity Swelling in Female Patients with Cancer. Samdani, Saima; Lachmann, Elisabeth; Nagler, Willibald // Journal of Women's Health & Gender-Based Medicine;May2001, Vol. 10 Issue 4, p319 

    Unilateral extremity swelling may be secondary to two major causes in female patients with cancer, deep venous thrombosis (DVT) and lymphedema. In women of all ages, DVT is high on the differential diagnosis list for unilateral extremity swelling. However, in women with an underlying malignancy,...

  • Protection by Flunarizine against Endothelial Cell Injury in vivo. Hladovec, J.; De Clerck, F. // Angiology;Jul1981, Vol. 32 Issue 7, p448 

    Flunarizine in vivo protects against endothelial cell damage induced by intravenous injection of citrate, CaCl2, or lactate in rats. Its effect is optimal at the low oral dose of 0.1 mg/kg, corresponding to the clinically used one. It lasts for at least 8 hours. Edema formation, platelet...

  • INFLUENCES OF TRYPSIN AND STREPTOKINASE ON INTRAVASCULAR CLOTTING. Kamiya, Kisaku; Fukuta, Kouzo // Angiology;Mar1961, Vol. 12 Issue 3, p105 

    Although trypsin and streptokinase have been considered valuable clinically for the treatment of thromboembolic diseases, the mechanism of their action has not been fully understand. Our experimental investigation has clarified the histologic changes brought about by these drugs and suggested...

  • Isolation and Characterization of the Human Inter- α-Trypsin Inhibitor Family Heavy Chain-Related Protein (IHRP) Gene (ITIHL1). Saguchi, Ken-ichi; Tobe, Takashi; Hashimoto, Ken; Nagasaki, Yuta; Oda, Eiichi; Nakano, Yasuko; Miura, Nam-Ho; Tomita, Motowo // Journal of Biochemistry;1996, Vol. 119 Issue 5, p898 

    Inter-α-trypsin inhibitor (ITI) family heavy chain-related protein (IHRP) is a novel human glycoprotein that shows significant homology in amino acid sequence to proteins of the ITI family heavy chains from human plasma. Three overlapping clones that encode the human inter-c-trypsin inhibitor...

  • Localization of human airway trypsin-like protease in the airway: an immunohistochemical study. Takahashi, Masako; Sano, Toshiaki; Yamaoka, Kazuyoshi; Kamimura, Takashi; Umemoto, Naoji; Nishitani, Hiromu; Yasuoka, Susumu // Histochemistry & Cell Biology;Mar2001, Vol. 115 Issue 3, p181 

    Human airway trypsin-like protease (HAT) has been isolated from mucoid sputum of patients with chronic airway diseases. In order to clarify the cellular source of this novel protease in the human airway, we examined the localization of immunoreactive HAT in bronchial tissues obtained at surgery...

  • Crystal Structure of Bovine Trypsin and Wheat Germ Trypsin Inhibitor (I-2b) Complex (2:1) at 2.3 Ã… Resolution1. Raj, S. Shanmuga Sundara; Kibushi, Eiji; Kurasawa, Tatsuhiro; Suzuki, Atsuo; Yamane, Takashi; Odani, Shoji; Iwasaki, Yugo; Yamane, Tsuneo; Ashida, Tamaichi // Journal of Biochemistry;2002, Vol. 132 Issue 6, p927 

    The Bowman-Birk trypsin inhibitor (BBI) from wheat germ (I-2b) consists of 123 amino acid residues with two inhibitory loops. The crystal structure of a bovine trypsin-wheat germ trypsin inhibitor (I-2b) complex (2:1) has been determined at 2.3 Ã… resolution to a final R-factor of 0.177. A...

  • Characterization Study of A Highly Specific Affinity Membrane For Trypsin Purification. Hamzah, Sofiah; Ali, Nora'aini; Ariffin, Marinah Mohd; Mohammad, Abdul Wahab // Applied Mechanics & Materials;2014, Issue 625, p592 

    This study aimed to characterize a highly specific affinity membrane for trypsin separation. The basic membrane was fabricated using 15% polysulfone via phase inversion technique. Membrane surface modification was employed by immersing the native membrane into the chitosan solution for 60...

  • Trypsin from the viscera of Bogue ( Boops boops): isolation and characterisation. Barkia, Ahmed; Bougatef, Ali; Nasri, Rim; Fetoui, Emna; Balti, Rafik; Nasri, Moncef // Fish Physiology & Biochemistry;Dec2010, Vol. 36 Issue 4, p893 

    Trypsin from the viscera of Bogue ( Boops boops) was purified to homogeneity by precipitation with ammonium sulphate, Sephadex G-100 gel filtration and Mono Q-Sepharose anion exchange chromatography, with an 8.5-fold increase in specific activity and 36% recovery. The molecular weight of the...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics