Jaques, William E.; Jones, E. Wynn; Campbell, Gilbert S.
February 1972
Angiology;Feb1972, Vol. 23 Issue 2, p89
Academic Journal
The ultrastructural changes in the pulmonary vasculature of calves with an aorta to pulmonary artery shunt are described. There was a progression of changes with time in those animals with a patent shunt. Animals in which the shunt was closed at one week demonstrated a return of the pulmonary vasculature to normal. Calves with the shunts closed at two weeks and a month revealed no regression of pulmonary vascular changes. Mast cells were increased in the adventitia of the pulmonary arterial system. It is postulated that mast cells may play an important role in the maintenance of the vascular lesions.


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