TITLE

ABNORMALITIES IN GLUCOSE TOLERANCE, LIPID AND LIPOPROTEIN LEVELS IN PATIENTS WITH ATHEROSCLEROTIC PERIPHERAL ARTERIAL DISEASE

AUTHOR(S)
Bliss, B. P.; Kirk, C. J. C.; Newall, R. G.
PUB. DATE
February 1972
SOURCE
Angiology;Feb1972, Vol. 23 Issue 2, p69
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Intravenous glucose tolerance and fasting non-esterified fatty acids, cholesterol, triglyceride and lipoprotein levels, together with fasting lipoprotein patterns, have been measured in a group of 50 patients with atherosclerotic peripheral arterial disease, and in a group of 20 healthy young adults. Reasons for taking healthy young adults as a control series rather than an age-matched group are discussed. The levels of each parameter have been classified into normal, borderline and abnormal ranges. 34% of patients had impaired glucose tolerance and 58% showed an elevation in fasting lipids. When borderline abnormalities are included the figures rose to 50% and 78% respectively. A definite abnormality of either glucose tolerance or fasting lipids was present in 66% of the series and the inclusion of borderline abnormalities makes this figure 88%. Only 6 patients (12%) had normal values for all parameters. When the disease group is compared with the control group, statistically significant reduction in glucose tolerance and elevation of fasting lipid levels is seen, the degree of significance being high in most instances.
ACCESSION #
16357746

 

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