Nakamura, Shozo; Kera, Kiyoshi; Sasaki, Ko; Takezawa, Yoshiaki
January 1972
Angiology;Jan1972, Vol. 23 Issue 1, p7
Academic Journal
Hepatic hemodynamics was investigated of 29 patients with idiopathic presinusoidal portal hypertension. Though the portal blood flow as a whole increased, the portal blood flowing through the liver remained within the normal range because of marked development of the extrahepatic shunted (portal) blood flow. The total hepatic blood flow also remained normal. The intrahepatic shunted blood flow increased slightly. The elevation of the wedged hepatic venous pressure was not so marked as in hepatic cirrhosis. Liver biopsy showed portal fibrosis and obstruction of the portal veins. Thus, portal hypertension in this disease cannot be explained by increase of the portal blood flow. Its primary cause seems to be increased resistance of the intrahepatic blood vessels, especially of the portal veins.


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