The Effect of β-Blockade on Leg Blood Flow in Hypertensive Patients with Intermittent Claudication

Boström, Per-Åke; Janzon, Lars; Ohlsson, Ola; Westergren, Anita
March 1986
Angiology;Mar1986 Part 1, Vol. 37 Issue 3, p149
Academic Journal
The present study was designed to assess the short-term effects of β-blocking antihypertensive treatment on leg blood flow in patients with peripheral artery disease. Seven patients with intermittent claudication were randomly allocated to treatment with atenolol 100 mg or pindolol 10 mg. Patients switched therapy after one month of treatment. Venous occlusion plethysmography on the calves was used to assess the effects on leg blood flow after one and two months of treatment. The average 10% reduction of the systolic and diastolic blood pressures was not associated with any reduction of blood flow at rest. There was on average 3.4 ml reduction of peak flow which had no influence on the painfree or total walking distance.


Related Articles

  • Commentary. Rudd, Peter // Evidence Based Medicine;Jun2006, Vol. 11 Issue 3, p85 

    The article comments on the medical research entitled "Review: Beta Blockers Are Less Effective Than Other Antihypertensive Drugs for Reducing Risk of Stroke in Primary Hypertension." In this study, the author suggests that clinicians should reconsider important comorbidities for individual...

  • Diabetes, hypertension, and antihypertensive agents. Pinkowish, Mary Desmond // Patient Care for the Nurse Practitioner;Jun2000, Vol. 3 Issue 6, p8 

    Discusses the results of the Atherosclerosis Risk in Communities study in the United States which deals with the risk of diabetes brought about by the use of beta-blockers in patients with hypertension. Description of the study; Difference between hypertensive patients taking and not taking...

  • Antihypertensive medication prescription patterns and time trends for newly-diagnosed uncomplicated hypertension patients in Taiwan. Pang-Hsiang Liu; Jung-Der Wang // BMC Health Services Research;2008, Vol. 8, Special section p1 

    Background: Knowledge of existing prescription patterns in the treatment of newly-diagnosed hypertension can provide useful information for improving clinical practice in this field. The aims of this study are to determine the prescription patterns and time trends for antihypertensive medication...

  • pindolol.  // Davis's Drug Guide for Nurses, 9th edition;2005, p849 

    Presents information on the antihypertensive and beta blocking agent pindolol. Use of the drug for the management of hypertension and angina pectoris; Actions and pharmacokinetics of the drug; Interactions with other drugs.

  • Patterns of antihypertensive medication use in hemodialysis patients. Rahman, Mahboob; Griffin, Valerie // American Journal of Health-System Pharmacy;7/15/2004, Vol. 61 Issue 14, p1473 

    Studies the pattern of antihypertensive drug use in patients undergoing long-term hemodialysis therapy. Frequency of hypertension in the participants; Percentage of the patients that were prescribed with calcium-channel blockers, angiotensin converting enzyme inhibitors and beta-blockers;...

  • Anti Hypertensive Prescribing Patterns and Cost Analysis for Primary Hypertension: A Retrospective Study. RACHANA, P. R.; ANURADHA, H. V.; SHIVAMURTHY, M. C. // Journal of Clinical & Diagnostic Research;Sep2014, Vol. 8 Issue 9, p19 

    Objective: The present study was conducted to analyze the current prescription pattern and cost analysis of antihypertensive drugs in hypertensive patients in a tertiary care hospital. Materials and Methods: A retrospective cross-sectional study was conducted in tertiary care hospital, Bangalore...

  • β blockers for heart failure with reduced ejection fraction. Waller, Derek G.; Waller, James R. // BMJ: British Medical Journal (Overseas & Retired Doctors Edition;10/1/2011, Vol. 343 Issue 7825, p691 

    The article offers information on the beta blockers for hormonal activation related to heart failure. It states that beta blockers are the drugs that block the action of the sympathetic nervous system of the heart, resulting in a relief of stress. It also informs that they cause side-effects...

  • The choice of antihypertensive therapy in patients with the metabolic syndrome—time to change recommendations?*. Hilgers, Karl F.; Mann, Johannes F. E. // Nephrology Dialysis Transplantation;Nov2008, Vol. 23 Issue 11, p3389 

    An editorial is presented which discusses the use of antihypertensive treatment in patients suffering from the metabolic syndrome. The authors cite the results of a study which challenged the application of thiazides and/or beta-blockers as second-line antihypertensive treatment in people with...

  • antihypertensive (Major drug group).  // Royal Society of Medicine: Medicines;2002, p73 

    The article presents information on antihypertensive drugs. These agents reduce hypertension and so reduce a patient's risk of heart attacks, kidney failure or stroke. If further treatment is necessary, any of the beta-blocker drugs may be used, with or without simultaneous administration of a...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics