TITLE

Therapeutic Efficacy of Alpha-Adrenoceptor Blockade in Primary and Secondary Raynaud's Syndrome

AUTHOR(S)
Cleophas, Ton J. M.; van Lier, Henk J. J.; Faaber, Peter; Fennis, Jan F. M.; van 't Laar, Albert
PUB. DATE
November 1984
SOURCE
Angiology;Nov1984, Vol. 35 Issue 11, p719
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Twenty patients with primary and U with secondary Raynaud's syndrome were treated with the alpha-adrenoceptor blocker phenoxybenzamine (10–20 mg daily). In the secondary group mean age and mean duration of symptoms as well as presence of positive ANA and positive Clq blinding test were significantly higher than in the primary group. In both groups a beneficial effect of the medication on finger temperature 12 min after finger cooling and on clinical symptoms was established. Secondary Raynaud's syndrome reacted at least as well as primary syndrome.
ACCESSION #
16352899

 

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