Hypereosinophilic Syndrome with Pulmonary Vascular Involvement

Hill, Ross; Nai-San Wang; Berry, Gerald
April 1984
Angiology;Apr1984, Vol. 35 Issue 4, p238
Academic Journal
We have studied a patient with hypereosinophilic syndrome (HES) who initially presented with recurrent asthmatic attacks followed by progressive dyspnea. Chronic obstructive lung disease was suspected at first although involvement of cardiac and other organ systems and marked eosinophilia eventually led to the diagnosis. Thereafter a diffuse interstitial pattern gradually developed on the chest radiograph which persisted despite vigorous treatment for cardiac failure. This was due to infiltration and cutting of the small pulmonary arteries by eosinophils. The bronchi showed changes consistent with asthma. Review of the literature indicates that this type of vascular change is common in HES but involves predominantly organs other than the lung. Similar pulmonary arterial changes have been produced experimentally in the calf by prolonged intravenous infusion of antibiotics, indicating that this may be a hypersensitivity reaction to a blood-borne material entering the pulmonary circulation.


Related Articles

  • Rare vascular anomaly mimicking bronchogenic carcinoma. Verma, Sanjeev Kumar; Mahajan, Vineet // Lung India;Apr-Jun2011, Vol. 28 Issue 2, p145 

    We report a case of anomalous left pulmonary artery (pulmonary artery sling) detected incidentally on computed tomography thorax. This was carried out to rule out bronchogenic carcinoma in a patient of chronic obstructive pulmonary disease who presented with streaking. He was a chronic smoker...

  • Reliability and Validity of Dyspnea Measures in Patients With Obstructive Lung Disease. Eakin, Elizabeth G.; Sassi-Dambron, Dawn E.; Ries, Andrew L.; Kaplan, Robert M. // International Journal of Behavioral Medicine;1995, Vol. 2 Issue 2, p118 

    Dyspnea, the clinical term for shortness of breath, is the primary symptom and an important outcome measure in evaluations of patients with lung disease. It is a subjective symptom that has proved difficult to quantify. Many dyspnea measures are available, yet it is difficult, based on the...

  • Approach To Swan Ganz Thermodilution Catheter Complications: 6 Years Experience With 2310 Cases. Karahan, Nagihan; Yetkin, Ufuk; Takut, Necmettin; Adanir, Tayfun; Aksun, Murat; Bayrak, Serdar; �zbek, Cengiz; G�rb�z, Ali // Internet Journal of Thoracic & Cardiovascular Surgery;2008, Vol. 11 Issue 2, p20 

    Aim: A pulmonary artery catheter is the most frequent material used during and after cardiac surgery to monitor the patient in the early period because it gives so much information to surgery and anesthesia teams and intensive care staff. To be knotted or fixation with atrium sutures are rare...

  • Pulmonary Artery Bronchial Fistula After Sleeve Lobectomy, A Case Report: A Fatal Complication Of Sleeve Lobectomy. Abe, Jiro; Kanma, Keiji; Saito, Yasuki // Internet Journal of Pulmonary Medicine;2002, Vol. 2 Issue 1, p1 

    A rare case of pulmonary artery bronchial fistula after sleeve lobectomy for lung cancer is described. Non-aspergillous ulcerative bronchitis was the most considerable cause of death in our case. The patient was once saved by emergency thoracotomy, but finally he died from recurrent massive...

  • The Pulmonary Artery in COPD -- Does Size Matter? Stanbrook, Matthew B. // New England Journal of Medicine;9/6/2012, Vol. 367 Issue 10, p946 

    The article discusses the association between pulmonary artery enlargement and increased risk of future exacerbations of chronic obstructive pulmonary disease (COPD) as reported by J. M. Wells et al. Pulmonary artery enlargement is defined as the diameter of the pulmonary artery on computed...

  • Need for chest radiography in acute exacerbation of COPD.  // American Family Physician;9/1/93, Vol. 48 Issue 3, p520 

    Discusses the incidence of abnormal chest radiographs in patients with acute exacerbation of chronic obstructive pulmonary disease (COPD) as cited in a study by Emerman and Cydulka in the April 1993 edition of `Annals of Emergency Medicine'. Abnormalities cited; Abnormalities in chest...

  • Doubled risk of CV event after COPD exacerbation.  // Pulse;5/12/2010, Vol. 70 Issue 16, p11 

    The article reports on the increased risk of cardiovascular occurrence in patients suffering from worsening Chronic Obstructive Pulmonary Disease (COPD).

  • FDA finds no increased cardiovascular risk in patients using tiotropium.  // Formulary;Feb2010, Vol. 45 Issue 2, p68 

    The article discusses the U.S. Food and Drug Administration finding that there was no increased cardiovascular risk associated with tiotropium use. Tiotropium bromide inhalation powder is used in the treatment of chronic obstructive pulmonary disease (COPD) and there had been concerns raised...

  • Improved cardiovascular flow quantification with time-resolved volumetric phase-contrast MRI. Hsiao, Albert; Alley, Marcus T.; Massaband, Payam; Herfkens, Robert J.; Chan, Frandics P.; Vasanawala, Shreyas S. // Pediatric Radiology;Jun2011, Vol. 41 Issue 6, p711 

    Background: Cardiovascular flow is commonly assessed with two-dimensional, phase-contrast MRI (2-D PC-MRI). However, scan prescription and acquisition over multiple planes is lengthy, often requires direct physician oversight and has inconsistent results. Time-resolved volumetric PC-MRI (4-D...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics