TITLE

LONG-TERM ADMINISTRATION OF RESERPINE IN HYPERTENSION

AUTHOR(S)
Kert, Morley J.; Penzell, Yale; Nordyke, Robert A.; Roth, Samuel I.; Smith, L. Allen; Westergart, Jack
PUB. DATE
October 1957
SOURCE
Angiology;Oct1957, Vol. 8 Issue 5, p466
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Reserpine was administered to a group of 79 out-patients with moderate to severe hypertension for as long as 34 months. Sixty per cent exhibited a significant fall in blood pressure and approximately 21 per cent of the entire group became normotensive. There were no serious toxic reactions but the incidence of undesirable side effects was high—approximately 70 per cent. Through adjustment of dosage or corrective medication these effects usually could be controlled. Nevertheless, almost 16 per cent of the group asked to have their medication discontinued. It is concluded that reserpine is a safe anti-hypertensive agent, worthy of trial in most hypertensives who do not present complications requiring urgent or drastic pressure reduction. In patients receiving other medications without a satisfactory hypotensive result, the addition of reserpine may bring about a further reduction in blood pressure.
ACCESSION #
16352084

 

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