TITLE

Role of Delayed Indium-111 Labeled Leukocyte Scan in the Management of Crohn's Disease

AUTHOR(S)
Slaton, G. D.; Navab, F.; Boyd, C. M.; Diner, W. C.; Texter Jr., E. C.
PUB. DATE
October 1985
SOURCE
American Journal of Gastroenterology;Oct1985, Vol. 80 Issue 10, p790
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Comparison of nine patients with Crohn's disease who had a positive delayed (24 hr) 111indium leukocyte scan and 10 patients with negative scan showed no significant difference between the two groups for the Crohn's disease activity index, sedimentation rate, survival, complications, number of days in hospital, outpatient visits, or readmissions. Despite the apparent lack of statistical significance in Crohn's disease activity index, the scan was positive in nine of 16 patients with a Crohn's disease activity index more than 150, and none of three patients with Crohn's disease activity index less than 150. In the patients studied, there were no false-positive leukocyte scans. In nine of 10 patients with ileocolonic disease, scanning results correctly predicted the proper management. Six patients with positive scan and enteroclysis responded to medical treatment. Four patients had positive enteroclysis and negative scan; of these, three had radiographic features of chronic ileal stricture which was confirmed at operation. The results suggest that a negative delayed indium-111 leukocyte scan may he useful in diagnosis of chronic fibrotic ileal stricture.
ACCESSION #
16351757

 

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