Valdivia, Enrique; Rowe, George G.; Usher, Michael
October 1967
Angiology;Oct1967, Vol. 18 Issue 10, p610
Academic Journal
Guinea pigs have been submitted to experimental chronic hypoxia in low pressure chambers. The pulmonary circulation has been studied by means of the injection of radiopaque material in the anesthetized animal. The chronic hypoxic animals do have a decreased capillary bed visualization and an increase in the pulmonary transit time. Return to sea level atmospheres shows improvement, but residual lesions remain. The described alteration may be secondary to polyeythemia and/or capillary lesions of the alveolar wall.


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