Hutchison, James C.; Kinlaw, W. Bernard; Kravitz, Bernard
April 1965
Angiology;Apr1965, Vol. 16 Issue 4, p187
Academic Journal
In summary then, we have studied in the Out-Patient Hypertensive Clinic at Abington Memorial Hospital 38 patients with an average of 56 years and 18 years duration of hypertension. Twenty-eight patients have completed the study. This consist of: a control period of approximately 4 weeks at which time their blood pressures were measured and their chemistries obtained. They were treated for approximately 5 weeks with the diuretic methyclothiazide at an average dose of 8 mg, and we found that there was a significant difference in their sitting, standing, and lying blood pressure while on this medication. We also noted that after 11 weeks of pargyline therapy at an average dose of 60 mg there was a significant difference in the sitting, standing and lying pressures from placebo. However, it was at the 99 per cent level in the sitting and standing positions, while only at the 95 per cent level in the lying position.


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