TITLE

New developments in the endoscopic surveillance of Barrett's oesophagus

AUTHOR(S)
Bergman, J. J. G. H. M.; Tytgat, G. N. J.
PUB. DATE
March 2005
SOURCE
Gut;Mar2005 Supplement 1, Vol. 54, pi38
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Patients with a Barrett's oesophagus are at risk for developing an adenocarcinoma of the distal oesophagus. Therefore, many patients undergo endoscopic surveillance to detect dysplasia and/or cancer at an early and curable stage. However, early neoplastic lesions are difficult to identify with standard endoscopy. In addition, the low incidence of these lesions, currently estimated at 0.5% per year, reduces the cost effectiveness of the surveillance strategy. New developments, aimed at improving the efficacy of Barrett's surveillance, focus on two areas: 1) improvement of the endoscopic detection of early neoplastic lesions; and 2) the use of alternative techniques !o tissue sampling combined with molecular markers to identify patients at risk for malignant degeneration.
ACCESSION #
16348821

 

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