TITLE

Opening of Coronary Collaterals by Repeated Brief Coronary Occlusions in Conscious Dogs

AUTHOR(S)
Fujita, Masatoshi; McKown, Daniel P.; McKown, Michael D.; Franklin, Dean
PUB. DATE
November 1988
SOURCE
Angiology;Nov1988, Vol. 39 Issue 11, p973
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The collateral blood flow and regional myocardial function during a one-minute coronary occlusion were compared before and after multiple one-minute coronary occlusions. After repeated coronary occlusions, the collateral blood flow velocity increased significantly from 0.7±0.1 (SE) to 2.0±0.2 cm/sec (p < 0.05), and the blood flow debt repayment decreased from 326±26% to 189±12% (p < 0.05). The systolic segment shortening in the collateral dependent zone improved slightly. Thus, the native coronary collateral vessels open in response to a repeated ischemic stimulus.
ACCESSION #
16347747

 

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