TITLE

SERUM LACTIC DEHYDROGENASE (LDH) ISOZYMES WITH ISCHEMIC DAMAGE OF SKELETAL MUSCLE OF THE HUMAN LIMB

AUTHOR(S)
Penneys, Raymond
PUB. DATE
November 1967
SOURCE
Angiology;Nov1967, Vol. 18 Issue 11, p678
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Serum lactic dehydrogenase isozymes, determined by the Wieme microelectrophoresis method, of four patients with acutely ischemic legs in which there was evidence of skeletal muscle damage showed definite cathodal bands that are characteristic of skeletal muscle. Patients with ischemic limbs but no muscle damage, and normal subjects, almost never showed such bands in their serum. Serum LDH isozymes are more specific for skeletal muscle damage than are the more commonly used enzymes, such as total LDH and GOT, and they can now be analyzed by practicable methods that lend themselves well to clinical practice.
ACCESSION #
16347076

 

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