Sandler, G.; Rickards, D. F.
January 1966
Angiology;Jan1966, Vol. 17 Issue 1, p31
Academic Journal
131I-Hippuran renograms have been recorded in 98 patients with primary or seondary hypertension. In 16 patients with primary hypertension in whom there was no evidence of renal impairment consistent renograms were obtained and the curves were used to establish ‘normal’ values as a basis for comparison with the remaining 82 hypertensive patients. Both absolute values for the different phases of the renogram (average of curves from the two kidneys) and the extent of the differences between curves from the right and left kidneys were calculated. Comparison was also made with the pyelographic findings in these 82 patients. In both primary and secondary hypertension the renogram was superior to the pyelogram in the detection of renal impairment although no correlation could be found with any specific phase of the renogram. The most useful diagnostic aid was finding a significant difference between the curves obtained from the right and left kidneys, in particular relating to the peak of the curve. The value of the renogram in detecting unilateral renal disease such as renal artery stenosis has also been confirmed. Finally, the study suggests that in hypertensive patients the renogram may be more sensitive in detecting renal impairment than the presence of albuminuria, a raised blood urea or reduced creatinine clearance.


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