Noninvasive Measurement of the Human Peripheral Circulation: Relationship Between Laser Doppler Flowmeter and Photoplethysmograph Signals from the Finger

Almond, Nicholas E.; Jones, Deric P.; Ernest D. Cooke
September 1988
Angiology;Sep1988, Vol. 39 Issue 9, p819
Academic Journal
Under certain conditions laser Doppler flowmeter (LDF) signals obtained from the finger pulp may appear very similar to those obtained by use of a direct current (dc) photoplethysmograph (PPG). A combined LDF/PPG system was used in conjunction with a circumference strain gauge as an index of volume change to identify the conditions in which the correlation between these signals was good. Simultaneous LDF and dc PPG measurements were made on 10 normal volunteers by using arterial occlusion and on 7 normal subjects by using the Valsalva maneuver at different elevations of the forearm and hand with respect to the midsternum. By altering the elevation of the upper limb the influence of venous filling on each of the signals during these maneuvers was observed. Since the dc PPG signal always appeared similar to the volume change indicated by the circumference strain gauge, it is concluded that the dc PPG signal is related to blood volume change if allowance is made for the effects of blood oxygenation. In circumstances of low venous filling, however, blood volume changes correlate well with blood flow changes, producing the correlation between the dc PPG and LDF traces. The dc PPG signal may be used as a means of monitoring changes in blood flow in the finger only when venous filling is low and the return remains unrestricted. Thus, in investigations using this method, the relative position of the limb with respect to the heart should always be indicated. The LDF method appears to be a reliable indicator of blood flow changes in the microcirculation irrespective of the degree of venous filling.


Related Articles

  • Monitoring the microcirculation in the critically ill patient: current methods and future approaches. De Backer, Daniel; Ospina-Tascon, Gustavo; Salgado, Diamantino; Favory, Raphaël; Creteur, Jacques; Vincent, Jean-Louis // Intensive Care Medicine;Nov2010, Vol. 36 Issue 11, p1813 

    Purpose: To discuss the techniques currently available to evaluate the microcirculation in critically ill patients. In addition, the most clinically relevant microcirculatory alterations will be discussed. Methods: Review of the literature on methods used to evaluate the microcirculation in...

  • Heat transfer analysis for peripheral blood flow measurement system. Nagata, Koji; Hattori, Hideharu; Sato, Nobuhiko; Ichige, Yukiko; Kiguchi, Masashi // Review of Scientific Instruments;Jun2009, Vol. 80 Issue 6, p064902 

    Some disorders such as circulatory disease and metabolic abnormality cause many problems to peripheral blood flow condition. Therefore, frequent measurement of the blood flow condition is bound to contribute to precaution against those disorders and to control of conditions of the diseases. We...

  • Evaluation of Blood Flow in Tumor Masses by Using 2D-Doppler Color Flow Mapping -- Case Reports. Itoh, Kouichi; Suzuki, Osamu; Yasuda, Yoshikazu; Aihara, Toshinori // Angiology;Sep1987, Vol. 38 Issue 9, p705 

    Blood flow in tumor masses was detected with 2D-Doppler color flow mapping in 3 cases; a pancreatic carcinoma in a sixty-five-year-old woman, a renal cell carcinoma in a sixty-two-year-old woman, and a chemodectoma in a sixty-six- year-old woman.

  • Laser Doppler Blood Flow Monitoring in Reconstructive Vascular Surgery: Case Studies. Svensson, Henry; Bergqvist, David; Takolander, Rabbe // Vascular Surgery;Jan/Feb1987, Vol. 21 Issue 1, p58 

    Laser Doppler flowmetric (LDF) measurements were performed preoperatively and postoperatively in patients undergoing arterial reconstruction in the lower limb, and intraoperatively in patients undergoing abdominal aortic reconstruction. In 21 instances of successful arterial reconstruction in...

  • Evaluation of microcirculation and wound-closing tension after undermining the skin. A study in a porcine model using laser Doppler perfusion imaging. T�nseth, Kim A.; Hokland, Bj�rn M. // European Journal of Plastic Surgery;Nov2004, Vol. 27 Issue 6, p295 

    Undermining the skin can reduce wound tension when closing skin defects and thereby can provide a potentially better microcirculation. On the other hand, undermining causes damage to blood vessels. In this study the relationship between wound tension and microcirculation in undermined wounds was...

  • Cutaneous Blood Flow in Aging Skin. Waller, Jeanette M.; Maibach, H. I. // Cosmetics & Toiletries;Jul2006, Vol. 121 Issue 7, p38 

    Discusses results from a literature search on age-related changes in cutaneous blood perfusion. In vivo methods, including the use of intravital capillaroscopy; Mixed results of studies using laser Doppler flowmetry and laser Doppler velocimetry; Details of photoplethysmography. INSET:...

  • Digital Blood Flow Response to Body Warming, Cooling, and Rewarming in Patients with Raynaud's Phenomenon. Lau, C. S.; Khan, F.; Brown, R.; McCallum, P.; Belch, J. J. F. // Angiology;Jan1995, Vol. 46 Issue 1, p1 

    Although the diagnosis of Raynaud's phenomenon (RP) is usually made easily from a careful history, the assessment of RP severity is difficult, for the vasopastic attacks are not easily induced under experimental conditions. In this study, the laser Doppler flowmetry (LDF) technique was used to...

  • Choroidal blood flow in the foveal region in eyes with rhegmatogenous retinal detachment and scleral buckling procedures. Sugawara, R.; Nagaoka, I.; Ktaya, N.; Fujio, N.; Takahashi, J.; Takahashi, A.; Yokota, H.; Yoshida, A. // British Journal of Ophthalmology;Nov2006, Vol. 90 Issue 11, p1363 

    Aims: To investigate changes in choroidal blood flow (ChBF) in the foveal region of the human eye with rhegmatogenous retina? detachment induced by scleral buckling. Methods: ChBF was measured in the foveal region using laser Doppler flowmetry in patients with a rhegmatogenous retinal detachment...

  • A Reduction in Intraovarian Blood Flow Resistance After Ovulation is Necessary Cycle. Nakagawa, Koji; Ozawa, Nobuaki; Takamatsu, Kiyoshi; Takahashi, Yuji; Irahara, Minoru; Yoshimura, Yasunori; Saito, Hidekazu // Journal of Assisted Reproduction & Genetics;Jan2005, Vol. 22 Issue 1, p9 

    Purpose: Color Doppler imaging permits the accurate localization of vessels and high-frequency pulsed Doppler ultrasonography has improved the resolution of flow velocity waveforms. In this study, intraovarian arterial blood flow before and after follicle rupture in the natural cycle was...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics