Treatment of Diabetic Neuropathy with Pentoxifylline: Case Report

Kalmansohn, Robert B.; Kalmansohn, Richard W.; Markham, Charles H.; Schiff, David L.
April 1988
Angiology;Apr1988, Vol. 39 Issue 4, p371
Academic Journal
Diabetic neuropathy includes a heterogenous group of neuropathic syndromes associated with diabetes mellitus. One form of diabetic neuropathy is distal symmetric polyneuropathy, which is characterized at a stage by intractable pain. This pain is generally refractory to present modalities of therapy except for narcotics. Pentoxifylline offers a new approach to therapy, reducing the blood viscosity and improving perfusion of ischemic microcirculation. A case report will be presented of intractable painful peripheral neuropathy responding dramatically to pentoxifylline therapy.


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