Noninvasvie Testing of Cerebral Perfusion Reserve Prior to Coronary Artery Bypass Graft Surgery

Levine, Ross L.; Lagreze, Hans L.; Berkoff, Herbert A.; Turnipseed, William D.; Hanson, Joan M.; Sunderland, John J.; Nickles, Robert J.; Rowe, Bruce R.
May 1988
Angiology;May1988, Vol. 39 Issue 5, p421
Academic Journal
Cerebral perfusion reserve testing using fluorine-18-fluoromethane and position emission tomographic brain scanning to define cerebral blood flow abnor- malities was performed in 5 patients being considered for combined coronary and carotid reconstructive surgery. Blood flow testing during normocapnia and following hypercapnia was utilized in these patients to determine the hemodynamic significance of known extracranial carotid artery occlusive lesions. Reserve diminution in 2 of these patients prompted combined surgery, whereas normal reserve values in the other 3 prompted coronary surgery alone. Results obtained in this preliminary series show how preoperative noninvasive testing of cerebral perfusion reserve adds to the diagnostic evaluation of patients with widespread vascular disease.


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