TITLE

A STUDY OF HUMAN AORTIC DISTENSIBILITY WITH RELATION TO ATHEROSCLEROSIS AND AGING

AUTHOR(S)
Nakashima, Teruyuki; Tanikawa, Junji
PUB. DATE
September 1971
SOURCE
Angiology;Sep1971, Vol. 22 Issue 8, p477
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Atherosclerosis has been thought for a long time to be proportionate to the arterial senility. And atheroselerotic changes in Caucasians, Boston, U. S. A. were ascertained by Gore, et al. to be much more severe than those in Japanese, Kyushu, Japan. The loss of arterial distensibility has also been thought to be an index of arterial senility with inseparable relation to atherosclerotic changes. It seems doubtful to us, however, that atherosclerosis is the index of arterial senility and can not be separable from the loss of arterial distensibility. We tried to clarify these relations among atherosclerosis, the loss of distensibility and aging, and found the results to be as follows: 1. The loss of human aortic distensibility progresses steadily with aging regardless of the atherosclerotic severity. 2. The severity of aortic atherosclerosis is not proportionate to the loss of aortic distensibility. The aorta which has severe atherosclerosis showed similar distensibility to the aorta with almost no atherosclerotic lesion in the same decade. 3. Contrary to the remarkable difference of atherosclerotic severity between Americans and Japanese, the loss of aortic distensibility of Americans does no seem bigger than that of the Japanese. They both show very similar distensibility in the same decades (5th and 6th decades). 4. We are impressed from these results that the atherosclerotic change should be separated pathologically from the loss of distensibility and the aortic senility would be shown by the latter. Atherosclerosis is only a disease which tends to occur in elderly person.
ACCESSION #
16330844

 

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