Barking up the wrong tree? Use of polymerase chain reaction to diagnose syphilitic aortitis

O'Regan, A. W.; Castro, C.; Lukehart, S. A.; Kasznica, J. M.; Rice, P. A.; Joyce-Brady, M. F.
October 2002
Thorax;Oct2002, Vol. 57 Issue 10, p917
Academic Journal
The presentation of syphilitic aortitis is often atypical and available serological tests are non-specific. The diagnostic gold standard remains direct identification of microorganisms in tissue. We present a case of syphilitic cortitis that presented as a mediastinal mass and report the use of polymerase chain reaction for Treponema pallidum to diagnose syphilitic aortic disease.


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