Diehl, A. M.; Z. P. Li; Tin, H. Z.; S. Q. Yang
February 2005
Gut;Feb2005, Vol. 54 Issue 2, p303
Academic Journal
This article presents a study related to cytokines and the pathogenesis of non-alcoholic steatohepatitis. Histopathological characteristics distinguish steatohepatitis from other causes of chronic liver injury. Obesity, especially visceral adiposity, is a major risk factor for NASH in humans. Even if they do not have an elevated body mass index, patients with NASH are very likely to be insulin resistant. Basic research on fat cell biology provides some clues about why obesity, insulin resistance, and NASH may be interrelated.


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