TITLE

Pancreatic Polypeptide (PP) Responses to Oral and Intravenous Glucose in Man

AUTHOR(S)
Sive, A. A.; Van Tonder, S. V.; Vinik, A. I.
PUB. DATE
February 1979
SOURCE
American Journal of Gastroenterology;Feb1979, Vol. 71 Issue 2, p183
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
Serum human pancreatic polypeptide (hPP) responses to 50 gm. of oral glucose and a 25 gm. intravenous bolus of glucose were measured in 10 healthy human volunteers. Oral glucose caused a 50% rise, whereas I.V. glucose caused a .3.5% fall in hPP concentration. There was no relationship between the absolute glucose concentration or the change in glucose level and the PP concentration. It is suggested that oral and I.V. glucose affect PP by indirect mechanisms and that PP may be involved in carbohydrate metabolism in man.
ACCESSION #
16133786

 

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