TITLE

Intestinal Herpes Simplex Infection Presenting with Intestinal Perforation

AUTHOR(S)
Wasselle, Joseph A.; Sedgwick, Jacqueline H.; Dawson, Peter J.; Fabri, Peter J.
PUB. DATE
October 1992
SOURCE
American Journal of Gastroenterology;Oct1992, Vol. 87 Issue 10, p1475
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
A 77-yr-old man who had received systemic steroids for more than 6 yr presented with an acute abdomen. Laparotomy revealed an ulcerative jejunitis with purulent peritonitis. The patient underwent resection of involved bowel followed by a 10-day course of aciclovir, with excellent results. Pathologic examination showed a necrotizing enteritis with intranuclear inclusions typical of Herpesvirus that reacted immunocytochemically with antibodies to herpes simplex virus types I and II. A rising herpes simplex virus serum antibody titer confirmed the diagnosis. Intestinal herpes infection with perforation should be added to the list of complications from herpes simplex in the immunocompromised patient.
ACCESSION #
16070238

 

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