Metastatic Tumors to the Upper Gastrointestinal Tract: Endoscopic Experience

Kadakia, Shailesh C.; Parker, Allan; Canales, Luis
October 1992
American Journal of Gastroenterology;Oct1992, Vol. 87 Issue 10, p1418
Academic Journal
Metastatic tumors to the upper gastrointestinal tract were identified by esophagogastroduodenoscopy in 14 patients. Malignant melanoma, breast cancer, and lung cancer were the most common primary cancers in four, three, and three patients, respectively. Osteogenic sarcoma, renal cell carcinoma, Meckel cell carcinoma of the skin, and germ-cell tumor were the primary cancer in the remaining four. The esophagus was involved in three patients, the stomach in 13, duodenum in four, and papilla of Vater in one. Upper gastrointestinal bleeding and anemia were the most common presenting features. There was correlation between symptoms and endoscopic findings in all patients. Involvement of gastrointestinal tract at endoscopy was the initial and only evidence of metastases in all patients without evidence of metastases elsewhere, as evidenced by other diagnostic tests in any of these patients. Endoscopic biopsies and/or brush cytology provided histologic diagnosis in all 14 patients. The endoscopic and nonendoscopic literature regarding metastases to the upper gastrointestinal tract is reviewed.


Related Articles

  • Review of clinical and endoscopic features of metastatic tumors of the gastrointestinal tract. Bashir, Showkat; Borum, Marie // Journal of Digestive Endoscopy;Apr-Jun2014, Vol. 6 Issue 1, p11 

    Metastatic tumors may occur at any site within the digestive tract. Most of these metastasis are observed in the stomach, small bowel, duodenum, and rarely in the esophagus and colon. The progress in cancer treatment, improved survival of cancer patients combined with increased use of endoscopy...

  • Endoscopic submucosal dissection (ESD) for gastrointestinal carcinoid tumors. Suzuki, Shoko; Ishii, Naoki; Uemura, Masayo; Deshpande, Gautam; Matsuda, Michitaka; Iizuka, Yusuke; Fukuda, Katsuyuki; Suzuki, Koyu; Fujita, Yoshiyuki // Surgical Endoscopy;Mar2012, Vol. 26 Issue 3, p759 

    Background: Gastrointestinal (GI) carcinoid tumors less than 10 mm in diameter and limited to the submucosal layer demonstrate a low frequency of lymph node and distant metastasis; endoscopic submucosal dissection (ESD) has been used to treat these tumors. However, the number of reported sample...

  • Immunohistochemical features of the gastrointestinal tract tumors. Wong, Hannah H.; Peiguo Chu // Journal of Gastrointestinal Oncology;2012, Vol. 3 Issue 3, p262 

    Gastrointestinal tract tumors include a wide variety of vastly different tumors and on a whole are one of the most common malignancies in western countries. These tumors often present at late stages as distant metastases which are then biopsied and may be difficult to differentiate without the...

  • Endoscopic submucosal dissection for gastrointestinal neoplasms. Kakushima, Naomi; Fujishiro, Mitsuhiro; Fireman, Zvi; Chee Lim // World Journal of Gastroenterology;5/21/2008, Vol. 14 Issue 19, p2962 

    Endoscopic submucosal dissection (ESD) is an advanced technique of therapeutic endoscopy for superficial gastrointestinal neoplasms. Three steps characterize it: injecting fluid into the submucosa to elevate the lesion, cutting the surrounding mucosa of the lesion, and dissecting the submucosa...

  • Laparoscopic approaches to resection of suspected gastric gastrointestinal stromal tumors based on tumor location. Privette, A.; McCahill, L.; Borrazzo, E.; Single, Richard M.; Zubarik, R. // Surgical Endoscopy;Feb2008, Vol. 22 Issue 2, p487 

    Surgical resection of gastric gastrointestinal stromal tumor (GIST) should be optimized to achieve a negative pathologic surgical margin while limiting the extent of stomach volume loss. Careful identification of exact gastric tumor location using preoperative computed tomography (CT) scans and...

  • Magnifying chromoendoscopic findings of early gastric cancer and gastric adenoma. Ohnita, Ken; Isomoto, Hajime; Shikuwa, Saburo; Yamaguchi, Naoyuki; Nakayama, Toshiyuki; Nishiyama, Hitoshi; Okamoto, Kenta; Fukuda, Eiichiro; Takeshima, Fuminao; Hayashi, Tomayoshi; Kohno, Shigeru; Nakao, Kazuhiko // Digestive Diseases & Sciences;Sep2011, Vol. 56 Issue 9, p2715 

    Purpose: In the field of colorectal cancer and adenoma, Kudo's classification of pit pattern with magnifying chromocolonoscopy using crystal violet (CV) staining is now accepted. Magnifying endoscopy using narrow band imaging has been used for the diagnosis of gastric carcinoma; the...

  • Autofluorescence imaging and magnification endoscopy. Filip, Monalisa; Iordache, Sevastiţa; Săftoiu, Adrian; Ciurea, Tudorel // Annals of Gastroenterology & Hepatology;2011, Vol. 9 Issue 97, p9 

    It is well known that angiogenesis is critical in the transition from premalignant to malignant lesions. Consequently, early detection and diagnosis based on morphological changes to the microvessels are crucial. In the last few years, new imaging techniques which utilize the properties of...

  • Systemic Therapy for Elderly Patients with Gastrointestinal Cancer. Hubbard, Joleen M.; Grothey, Axel; Sargent, Daniel J. // Clinical Medicine Insights: Oncology;2011, Issue 5, p89 

    The majority of patients with gastrointestinal cancers are over the age of 65. This age group comprises the minority of the patients enrolled in clinical trials, and it is unknown whether older patients achieve similar results as younger patients in terms of survival benefit and tolerability. In...

  • Enhanced magnifying endoscopy for differential diagnosis of superficial gastric lesions identified with white-light endoscopy. Tao, Guo; Xing-hua, Lu; Ai-ming, Yang; Wei-xun, Zhou; Fang, Yao; Xi, Wu; Li-yin, Wang; Chong-mei, Lu; Gui-jun, Fei; Hui-jun, Shu; Dong-sheng, Wu; Yue, Li; Xiao-qing, Li; Jia-ming, Qian // Gastric Cancer;Jan2014, Vol. 17 Issue 1, p122 

    Background: Various techniques using magnifying endoscopy (ME) and chromoendoscopy are being developed to enhance images of gastrointestinal tumor. The aim of this study was to evaluate the diagnostic performance of ME enhanced by acetic acid-indigo carmine mixture (ME-AIM) and ME enhanced with...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics