Intravaginal and intrarectal microbicides to prevent HIV infection

Balzarini, Jan; Van Damme, Lut
February 2005
CMAJ: Canadian Medical Association Journal;2/15/2005, Vol. 172 Issue 4, p461
Academic Journal
Analyzes the therapeutic use of intravaginal and intrarectal microbicides for preventing HIV infection. Potential mechanisms for HIV transmission across mucosal epithelium; Discussion on the buffering agents and detergents that comprise nonspecific microbicides; Investigation of a variety of anionic substances that target the adsorption and fusion process of the virus; Mechanism of action of HIV-specific microbicides.


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