TITLE

COMMENTARY: Loop diuretics and angiotensin-converting enzyme inhibitors increased risk for hospitalization for lithium toxicity

AUTHOR(S)
Laville, Maurice
PUB. DATE
January 2005
SOURCE
ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p25
SOURCE TYPE
Academic Journal
DOC. TYPE
Article
ABSTRACT
The article reports that loop diuretics and angiotensin-converting enzyme inhibitors increased risk for hospitalization for lithium toxicity. Older patients with decreased glomerular filtration rate are at risk for renal insufficiency after diuretic-induced volume contraction, and it is likely that patients treated with long-term lithium are at higher risk for toxicity because of tubular damage and impaired sodium reabsorption. The shorter effect of furosemide is followed by large sodium-avid periods.
ACCESSION #
15851803

 

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