Review: Limited evidence supports the use of atypical antipsychotic drugs in behavioral and psychological symptoms of dementia

Lee, P.
January 2005
ACP Journal Club;Jan/Feb2005, Vol. 142 Issue 1, p15
Academic Journal
The article reports that limited evidence supports the use of atypical antipsychotic drugs in behavioral and psychological symptoms of dementia. Efficacy was assessed by scores on the Behavior pathology in Alzheimer s Disease, Cohen-Mansfield Agitation Inventory and Neuropsychiatrie Inventory-nursing home version scales. In patients with behavioral and psychological symptoms of dementia, limited evidence supports the effectiveness of atypical antipsychotic drugs.


Related Articles

  • Increased mortality among elderly patients with dementia using atypical antipsychotics. Singh, Sonal; Wooltorton, Eric // CMAJ: Canadian Medical Association Journal;8/2/2005, Vol. 173 Issue 3, p252 

    Discusses research being done on the use of atypical anti-psychotic drugs in the treatment of behavioral and psychological symptoms of dementia. Reference to a study by P. E. Lee, S. S. Freedman et al, published in the 2004 issue of the "British Medical Journal"; Incidence of death among...

  • Use of Atypical Antipsychotic Drugs in Patients with Dementia. Motsinger, Charles D.; Perron, Gregory A.; Lacy, Timothy J. // American Family Physician;6/1/2003, Vol. 67 Issue 11, p2335 

    Assesses the use of atypical antipsychotic drugs in patients with dementia. Background on atypical antipsychotic drugs; Treatment of behavior disturbances; Examples of typical antipsychotic drugs.

  • Death risk drugs.  // Mental Health Today;Jun2005, p7 

    Reports on the research findings of the Alzheimer's Society as of 2005, that potentially fatal neuroleptic drugs are still being prescribed to elderly people with dementia after being banned in Great Britain in 2004. Information on the rule of the Committee on Safety of Medicines, banning...

  • Antipsychotics.  // Reactions Weekly;Mar2014, Vol. 1493 Issue 1, p10 

    The article presents case studies of six women and seven men who developed neuroleptic malignant syndrome while receiving treatment with antipsychotics. It is reported that the patients were receiving treatment for schizophrenia, affective disorders, organic mental disorder or disorder of adult...

  • Review: atypical antipsychotics may be useful in treating behavioural and psychological symptoms of dementia but cause adverse effects. Tariot, Pierre N. // Evidence Based Mental Health;Feb2005, Vol. 8 Issue 1, p16 

    The article presents a study on the effectiveness of atypical antipsychotics in treating behavioral and psychological symptoms of dementia. Researchers observed that at 6-12 weeks, both risperidone and olanzapine significantly reduced scores for BPSD compared with placebo in four trials. Limited...

  • Old vs new: which antipsychotics should be used?  // Reactions Weekly;9/3/2005, Issue 1067, p5 

    Discusses research being done on the efficacy and tolerability of conventional and modern antipsychotics. Reference to a study by David M. Gardner et al published in the June 21, 2005 issue of the "Canadian Medical Association Journal"; Difference between conventional and modern antipsychotics;...

  • QOF could cut antipsychotic use for dementia patients. Robinson, Stephen // GP: General Practitioner;2/1/2012, p14 

    The article reports that according to a research, antipsychotic prescribing for dementia need to be reviewed as part of the qality and outcomes famework (QOF) to slash inappropriate use of the drugs. The study found that of patients with dementia were prescribed antipsychotics despite high rates...

  • Drug review warns on use of antipsychotics. Baines, Emma // GP: General Practitioner;3/15/2004, p14 

    The Medicines and Healthcare Products Regulatory Agency (MHRA) has warned that the atypical antipsychotics risperidone and olanzapine should not be used to treat behavioral problems in elderly patients with dementia. The advice comes in the light of a drug safety review carried out by the...

  • Ethical dilemmas: should antipsychotics ever be prescribed for people with dementia? Treloar, Adrian; Crugel, Monica; Prasanna, Aparna; Solomons, Luke; Fox, Chris; Paton, Carol; Katona, Cornelius // British Journal of Psychiatry;Aug2010, Vol. 197 Issue 2, p88 

    The use of antipsychotics for the treatment of behavioural and psychological symptoms of dementia (BPSD) is controversial. Antipsychotics cause harm and evidence-based guidelines advise against their use. We argue that antipsychotics may be justified using a palliative model: by reducing severe...


Read the Article


Sorry, but this item is not currently available from your library.

Try another library?
Sign out of this library

Other Topics